Biolina Plus 2.5 mg+850 mg (Tablet)
Unit Price: ৳ 13.50 (2 x 6: ৳ 162.00)
Strip Price: ৳ 81.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linagliptin metformin hydrochloride |
| Company | Biogen pharmaceuticals ltd |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibitor of DPP-4
- Increases active incretin hormones
- Stimulates insulin release
- Decreases glucagon secretion
- Oral antihyperglycemic drug
- Lowers plasma glucose
- Improves insulin sensitivity
- Decreases hepatic glucose production
- Decreases intestinal glucose absorption
Dosage & Administration
- Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals
- Dose escalation should be gradual
- Recommended starting dose for new and current Metformin users
- Dosage for extended release tablet
Interaction
- Cationic drugs interaction
- Carbonic Anhydrase Inhibitors interaction
- Inducers of P-glycoprotein and CYP3A4 Enzymes interaction
- Drugs affecting glycemic control interaction
Contraindications
- Renal impairment
- Acute or chronic metabolic acidosis
- Hypersensitivity to Linagliptin or Metformin Hydrochloride
Side Effects
- Nasopharyngitis
- Diarrhea
- Hypoglycemia
Pregnancy & Lactation
- Use only if clearly needed
- Caution during lactation
Precautions & Warnings
- Lactic acidosis risk
- Acute pancreatitis reports
- Discontinuation for radiologic studies or surgical procedures
- Vitamin B12 monitoring
- Symptoms of lactic acidosis and pancreatitis
Overdose Effects
- Supportive measures
- Dialyzable Metformin Hydrochloride
- No dose-related clinical adverse drug reactions for Linagliptin
- Hypoglycemia and lactic acidosis in Metformin Hydrochloride overdose
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Cool & dry place
- Below 30°C
- Protected from light & moisture
- Keep out of the reach of children