Formet L 2.5 mg+500 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linagliptin metformin hydrochloride |
| Company | Biopharma limited |
Indications
- Adjunct to diet and exercise
- Improve glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibitor of DPP-4
- Stimulates insulin release
- Decreases glucagon secretion
- Lowers basal and postprandial plasma glucose
Dosage & Administration
- Individualized dosage
- Maximum recommended dose 2.5mg Linagliptin and 1000mg Metformin Hydrochloride twice daily with meals
- Gradual dose escalation to reduce GI side effects
Interaction
- Cationic drug interaction
- Carbonic Anhydrase Inhibitors interaction
- Inducers of P-glycoprotein and CYP3A4 Enzymes interaction
- Drugs affecting glycemic control interaction
Contraindications
- Renal impairment
- Acute or chronic metabolic acidosis (diabetic ketoacidosis)
- Hypersensitivity to Linagliptin or Metformin Hydrochloride
Side Effects
- Nasopharyngitis
- Diarrhea
- Hypoglycemia
Pregnancy & Lactation
- Caution during pregnancy
- Caution during lactation
Precautions & Warnings
- Discontinue in case of lactic acidosis
- Discontinue in case of suspected pancreatitis
- Temporary discontinuation for radiologic studies or surgical procedures
- Annual monitoring of hematologic parameters
Overdose Effects
- Supportive measures for overdose
- Unlikely removal of Linagliptin by dialysis
- Dialyzable Metformin Hydrochloride
- No dose-related clinical adverse drug reactions
Therapeutic Class
- Oral hypoglycemic preparations
Storage Conditions
- Cool & dry place below 30°C
- Protected from light & moisture
- Keep out of reach of children