Ligend M 2.5 mg+500 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Indications

  • Adjunct to diet and exercise
  • Improves glycemic control
  • Type 2 diabetes mellitus

Pharmacology

  • Inhibitor of DPP-4 enzyme
  • Increases incretin hormones
  • Stimulates insulin release
  • Decreases glucagon secretion
  • Oral antihyperglycemic drug
  • Lowers plasma glucose
  • Improves insulin sensitivity

Dosage & Administration

  • Linagliptin & Metformin immediate release tablet
  • Maximum recommended dose
  • Dose escalation
  • Starting dose for patients not treated with Metformin
  • Starting dose for patients already treated with Metformin
  • Switching from individual components to combination
  • Linagliptin & Metformin extended release tablet
  • Maximum recommended total daily dose
  • Recommended starting dose for different patient groups

Interaction

  • Cationic drugs interaction
  • Carbonic Anhydrase Inhibitors interaction
  • Inducers of P-glycoprotein and CYP3A4 Enzymes interaction
  • Drugs affecting glycemic control interaction

Contraindications

  • Renal impairment
  • Metabolic acidosis
  • Hypersensitivity to components

Side Effects

  • Nasopharyngitis
  • Diarrhea
  • Hypoglycemia
  • Sulfonylureas interaction

Pregnancy & Lactation

  • Use during pregnancy if clearly needed
  • Caution during lactation

Precautions & Warnings

  • Discontinuation in lactic acidosis
  • Discontinuation in pancreatitis
  • Discontinuation for radiologic studies and surgical procedures
  • Monitoring of Vitamin B12 levels
  • Symptoms of lactic acidosis
  • Alcohol consumption precautions
  • Other medicines precautions
  • Counseling
  • Travel precautions
  • Emergency preparedness
  • Hypoglycemia monitoring and treatment

Overdose Effects

  • Supportive measures
  • Removal of unabsorbed material
  • Supportive treatment
  • Hemodialysis or peritoneal dialysis for Metformin overdose
  • No dose-related adverse drug reactions for Linagliptin overdose
  • Symptoms and effects of Metformin overdose

Therapeutic Class

  • Oral hypoglycemic preparations

Storage Conditions

  • Cool and dry place
  • Protected from light and moisture
  • Keep out of the reach of children

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