Lacicard 2 mg (Tablet)
Unit Price: ৳ 4.00 (6 x 10: ৳ 240.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Lacidipine |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of hypertension
- Treatment in combination with other antihypertensive agents
Pharmacology
- Inhibition of calcium influx into smooth muscle cells
- Competitive inhibition of voltage-dependent calcium 'L' channels
Dosage & Administration
- Recommended initial dose of 2 mg once daily
- Possible dose increase to 4 mg and then 6 mg after 3 to 4 weeks
- Preferred administration in the morning
Interaction
- Potential increase in plasma concentration with simultaneous administration of cimetidine
- No identified pharmacodynamic interaction problems with common antihypertensive agents, digoxin, tolbutamide, or warfarin
Contraindications
- Hypersensitivity to any ingredient
- Cardiogenic shock
- Unstable angina
- Aortic stenosis
- Avoid within 1 month of myocardial infarction
- Impaired left ventricular function
Side Effects
- Flushing
- Palpitation
- Edema
- Headache
- Dizziness
- Gastro-intestinal disturbances
- Gum hyperplasia
- Mood disturbances
- Asthenia
- Polyuria
- Muscle cramps
- Skin rash
Pregnancy & Lactation
- No data on safety in human pregnancy
- No evidence of teratogenic effect in animal study
- Transfer into breast milk likely in animals
- Not recommended for use during pregnancy or lactation
Precautions & Warnings
- Cardiac conduction abnormalities
- Poor cardiac reserves
- Hepatic impairment
- Withdrawal if ischemic pain occurs shortly after initiating treatment or if cardiogenic shock develops
- Avoid grapefruit juice
Use in Special Populations
- No data on safety or efficacy in neonates
- Not evaluated in children
- Severe hepatic impairment: Reduce dose
Overdose Effects
- Prolonged peripheral vasodilation associated with hypotension and tachycardia
- Bradycardia or prolonged AV conduction
- Symptomatic and supportive treatment for management
Therapeutic Class
Calcium-channel blockers
Storage Conditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep out of the reach of children