Zolium XR 2 mg (Tablet (Extended Release))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Title and Categories

  • Zolium XR
  • Benzodiazepine Sedatives

Indications

  • Anxiety Disorder
  • Short term relief of anxiety
  • Anxiety associated with depression
  • Panic disorder, with or without agoraphobia

Pharmacology

  • Alprazolam
  • Triazole analog
  • 1,4-benzodiazepine class of drugs
  • Anxiolytic
  • Hypnotic
  • Anticonvulsive
  • Gamma Aminobutyric Acid (GABA)- benzodiazepine receptor complex interaction
  • CNS depressant activity

Dosage & Administration

  • Initiating dose of 0.25 to 0.5 mg three times daily
  • Maximum dose not to exceed 4 mg/day
  • Individualized dosage for maximum beneficial effect
  • Gradual dosage reduction when discontinuing therapy
  • Starting dose of 0.25 mg in elderly patients or patients with advanced liver disease
  • Administration of Alprazolam 1 mg once daily in the morning

Interaction

  • CNS-depressant action aggravation by concomitant use of other psychotropic drugs, anticonvulsants, antihistaminics, alcohol, and oral contraceptives

Side Effects

  • Side effects generally observed at the beginning of therapy
  • Most frequent side effects: drowsiness and light-headedness
  • Other potential side effects: depression, headache, confusion, dry mouth, constipation

Pregnancy & Lactation

  • Pregnancy category D - to be avoided in pregnancy
  • Assumed excretion in breast milk - nursing not recommended

Precautions & Warnings

  • Potential for psychological and physical dependence
  • Caution in patients with hepatic or renal disease, chronic pulmonary insufficiency, or sleep apnea

Use in Special Populations

  • Safety and effectiveness not established in individuals below 18 years of age

Overdose Effects

  • Manifestations of overdosage: somnolence, confusion, impaired coordination, diminished reflexes, and coma
  • Employment of general supportive measures and immediate gastric lavage in cases of overdosage

Therapeutic Class

  • Benzodiazepine sedatives

Storage Conditions

  • Below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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