Bizoran 10 mg+20 mg (Tablet)

Unit Price: ৳ 15.00 (2 x 15: ৳ 450.00)
Strip Price: ৳ 225.00

Medicine Details

Indications

  • Treatment of hypertension alone or with other antihypertensive agents
  • Lowering blood pressure
  • Initial therapy in patients likely to need multiple antihypertensive agents

Pharmacology

  • Dihydropyridine calcium channel blocker (Amlodipine)
  • Peripheral arterial vasodilator
  • Selective blocking of angiotensin II to the AT1 receptor (Olmesartan Medoxomil)

Dosage & Administration

  • Substitute individually titrated components
  • Initial therapy with 5/20 mg once daily for 1 to 2 weeks
  • Maximum dosage of 10/40 mg once daily

Interaction

  • Attenuation of antihypertensive effect by NSAIDs including selective COX-2 inhibitors
  • Closely monitoring of blood pressure, renal function, and electrolytes

Contraindications

  • Co-administration with Aliskiren in patients with diabetes

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Sprue-like enteropathy

Pregnancy & Lactation

  • Pregnancy Category D
  • Avoid use in 2nd and 3rd trimester
  • Discontinuation when pregnancy is detected

Precautions & Warnings

  • Caution in volume- or salt-depleted patients
  • Caution in patients with severe aortic stenosis
  • Caution in patients with severe obstructive coronary artery disease

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No overall differences in safety or effectiveness in geriatric use
  • Lack of studies in patients with renal impairment
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • No information available on overdose effects in humans

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Store below 30°C
  • Keep away from light
  • Keep out of reach of children

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