Bizoran 10 mg+40 mg (Tablet)

Unit Price: ৳ 22.00 (2 x 15: ৳ 660.00)
Strip Price: ৳ 330.00

Medicine Details

Indications

  • Treatment of hypertension
  • Lowering blood pressure
  • Initial therapy for multiple antihypertensive agents
  • Individualized blood pressure goals

Pharmacology

  • Dihydropyridine calcium channel blocker
  • Inhibits transmembrane influx of calcium ions
  • Peripheral arterial vasodilator
  • Blocks vasoconstrictor and aldosterone-secreting effects

Dosage & Administration

  • Substitute individually titrated components
  • Initial therapy with 5/20 mg once daily
  • Titration up to a maximum of 10/40 mg once daily
  • Recommended starting dose of Amlodipine is 2.5 mg in elderly patients

Interaction

  • Attenuation of antihypertensive effect by NSAIDs
  • Monitor blood pressure, renal function, and electrolytes

Contraindications

  • Co-administration with Aliskiren in patients with diabetes

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Sprue-like enteropathy

Pregnancy & Lactation

  • Pregnancy Category D
  • Contraindicated in 2nd and 3rd trimester
  • Potential excretion in human milk

Precautions & Warnings

  • Risk of hypotension in volume- or salt-depleted patients
  • Risk of vasodilation in patients with severe aortic stenosis
  • Risk of increased frequency, duration, or severity of angina or acute MI in patients with severe obstructive coronary artery disease

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No overall differences observed in subjects 65 years of age or older
  • No studies in patients with renal impairment
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • No information on overdose in humans

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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