Esonor 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 4.50 (5 x 10: ৳ 225.00)
Strip Price: ৳ 45.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Rn pharmaceuticals |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Treatment of acid-related Dyspepsia
- Treatment of Duodenal and Gastric ulcer
Pharmacology
- Proton pump inhibitor
- Suppression of gastric acid secretion
- Inhibition of H+/K+-ATPase
- Enteric-coated pellet formulation
- Peak plasma levels at approximately 1.5 hours
- Metabolized in the liver by the CYP enzyme system
Dosage
- Oral dosage form
- Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
- Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
- Symptomatic GERD: 20 mg Once Daily for 4 Weeks
- Helicobacter Pylori eradication: Triple Therapy for 10 days
- Zollinger-Ellison Syndrome: 20-80 mg once daily
- Acid-related Dyspepsia: 20-40 mg once daily
- Duodenal ulcer: 20 mg once daily for 2-4 weeks
- Gastric ulcer: 20-40 mg once daily for 4-8 weeks
- IV Injection or IV infusion for different patient groups
Administration
- Tablet or capsule should be swallowed whole
- Oral Suspension requires mixing with water
- IV Injection requires reconstitution and administration over a period of 3 minutes
Interaction
- Metabolized by CYP2C19 and CYP3A4
- No clinically relevant interactions with specific drugs
- Potential interference with CYP2C19 and gastric pH dependent drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Animal studies show no teratogenic effects
- Excretion in milk not studied
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Information for patients about capsule administration and use of antacids
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
- No overall differences in safety and efficacy in geriatric use
- No dosage adjustment recommended for mild to moderate hepatic insufficiency
- Pharmacokinetics not expected to be altered in renal impairment
Overdose Effects
- Lethal dose observed in rats
- Signs of acute toxicity
- No specific antidote known
Storage Conditions
- Temperature not exceeding 30°C
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
Common Questions about Esonor 20 mg Tablet
- Proton pump inhibitor reducing stomach acid production
- Treatment for GERD, ulcers, and other conditions
- List of common side effects
- Not studied for pregnancy and breastfeeding
- Information on time to onset of action
- Quick tips for taking Esonor 20 mg Tablet