Esonor 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 4.50 (5 x 10: ৳ 225.00)
Strip Price: ৳ 45.00

Medicine Details

Category Details
Generic Esomeprazole
Company Rn pharmaceuticals

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of Duodenal and Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Metabolized in the liver by the CYP enzyme system

Dosage

  • Oral dosage form
  • Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
  • Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
  • Symptomatic GERD: 20 mg Once Daily for 4 Weeks
  • Helicobacter Pylori eradication: Triple Therapy for 10 days
  • Zollinger-Ellison Syndrome: 20-80 mg once daily
  • Acid-related Dyspepsia: 20-40 mg once daily
  • Duodenal ulcer: 20 mg once daily for 2-4 weeks
  • Gastric ulcer: 20-40 mg once daily for 4-8 weeks
  • IV Injection or IV infusion for different patient groups

Administration

  • Tablet or capsule should be swallowed whole
  • Oral Suspension requires mixing with water
  • IV Injection requires reconstitution and administration over a period of 3 minutes

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically relevant interactions with specific drugs
  • Potential interference with CYP2C19 and gastric pH dependent drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Information for patients about capsule administration and use of antacids

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established
  • No overall differences in safety and efficacy in geriatric use
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in renal impairment

Overdose Effects

  • Lethal dose observed in rats
  • Signs of acute toxicity
  • No specific antidote known

Storage Conditions

  • Temperature not exceeding 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Esonor 20 mg Tablet

  • Proton pump inhibitor reducing stomach acid production
  • Treatment for GERD, ulcers, and other conditions
  • List of common side effects
  • Not studied for pregnancy and breastfeeding
  • Information on time to onset of action
  • Quick tips for taking Esonor 20 mg Tablet

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