Balovir 40 mg (Tablet)
1 tablet pack: ৳ 360.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Baloxavir marboxil |
| Company | Acme laboratories ltd |
Indications
- Treatment of acute uncomplicated influenza in patients 12 years of age and older
- Post-exposure prophylaxis (PEP) of influenza
- Symptomatic for no more than 48 hours
- Otherwise healthy
- At high risk of developing influenza-related complications
Pharmacology
- Antiviral polymerase endonuclease inhibitor
- Film-coated tablet for oral administration
- Active component: Baloxavir Marboxil
- Prodrug converted to Baloxavir by hydrolysis
- Inhibits the endonuclease activity of the polymerase acidic (PA) protein
- Required for viral gene transcription
- Inhibition of influenza virus replication
Dosage & Administration
- Single dose orally within 48 hours of symptom onset
- Dose depends on weight
- 40 to less than 80 kg: Two 20 mg tablets
- Total single dose of 40 mg
- At least 80 kg: Two 40 mg tablets
- Total single dose of 80 mg
- Pediatric patients 12 years of age and older weighing at least 40 kg
Interaction
- Avoid coadministration with dairy products
- Avoid coadministration with calcium-fortified beverages
- Avoid coadministration with polyvalent cation-containing laxatives
- Avoid coadministration with antacids
- Avoid coadministration with oral supplements (e.g., calcium, iron, magnesium, selenium, or zinc)
- Live attenuated influenza vaccines may be affected by antivirals
Contraindications
- History of hypersensitivity to Baloxavir Marboxil or any of its ingredients
Side Effects
- Diarrhea
- Bronchitis
- Nausea
- Sinusitis
- Headache
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Risks to the mother and fetus associated with influenza virus infection in pregnancy
- No data on the presence of baloxavir marboxil in human milk
- Effects on the breastfed infant
- Effects on milk production
Precautions & Warnings
- Hypersensitivity such as anaphylaxis, angioedema, urticaria, and erythema multiforme
- Risk of bacterial infection
- Not shown to prevent complications of secondary bacterial infections
Overdose Effects
- Treatment consists of general supportive measures
- Monitoring of vital signs
- Observation of the clinical status
- No specific antidote for overdose with Balovir
Therapeutic Class
- Respiratory viral infections (Influenza)
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children