D-Cap 2000 IU (Capsule)

Type of Product

• Vitamin D3 Supplement

Categories

• Vitamins and Minerals
• Bone Health

Color Options

• None

Dosage Form

• Capsule
• Film-Coated Tablet
• Oroflash or Chewable Tablet
• Syrup
• Injection

Dosage

• 40000 IU once weekly for 7 weeks (Adults)
• 1400-2000 IU/day for maintenance therapy (Adults)
• 20000 IU every 4 weeks for prevention (Adults)
• 20000 IU once a month for osteoporosis (Adults)
• 20000 IU once every 2 weeks for 6 weeks (Children 12-18 years)
• 20000 IU every 6 weeks for prevention (Children 12-18 years)
• 1000 IU (1-2 tablets) daily for film-coated tablet
• 1000-2000 IU daily for oroflash or chewable tablets
• 400 IU/ day for infants (0-1 yr) with risk of Cholecalciferol deficiency
• 600 lU/ day for children (>1 yr) with risk of Cholecalciferol deficiency
• 2000 IU/ day for 6 weeks for Cholecalciferol deficient patients (0-1 yr)
• 2000 IU/ day for 6 weeks for Cholecalciferol deficient patients (1-18 yrs)
• Injection every 6 months for infants receiving Vitamin D enriched milk
• Injection every 6 months for nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age
• Injection every 6 months for adolescents
• Injection from the 6th or 7th month of pregnancy for pregnant women
• Injection every 3 months for elderly with digestive disorders, concomitant treatment with antiepileptics & other particular conditions

Age Group

• Adults
• Children (12-18 years)
• Infants (0-1 yr)
• Children (>1 yr)

Usability Features

• Essential for healthy bones and teeth
• Prevents rickets, osteomalacia, and osteoporosis
• Boosts immunity
• Essential for a growing infant
• Vital role in preventing pre-eclampsia during pregnancy and breastfeeding
• Increases calcium absorption

Mode of Action

• Binds to Vitamin D receptors (VDRs)
• Absorbed in the small intestine
• Metabolized to 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3
• Fat soluble
• Stored in tissues such as fat and muscle
• Eliminated via faeces and urine

Interactions

• Interferes with drugs such as Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil, and Corticosteroids

Contraindications

• Hypercalcaemia
• Known hypersensitivity to Vitamin D3
• Evidence of Vitamin D3 toxicity

Side Effects

• Anorexia
• Lassitude
• Nausea & vomiting
• Diarrhea
• Constipation
• Weight loss
• Polyuria
• Sweating
• Headache
• Thirst
• Vertigo
• Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

• Safe use up to 4000 IU during pregnancy
• Recommended daily intake for pregnant women: 400 IU
• Vitamin D3 and its metabolites are excreted in breast milk
• Overdose in infants induced by nursing mothers has not been observed

Precautions & Warnings

• Monitor plasma-calcium concentration in patients receiving high doses
• Consult a health care practitioner before supplementing with Vitamin D3 if using Digoxin and Thiazide Diuretics
• Consult a health care practitioner before supplementing with Vitamin D3 if having liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis, or granulomatous disease

Special Populations

• Safety & efficacy not established in children under 12 years

Therapeutic Class

• Vitamin in bone formation
• Vitamin-D preparations

Storage Conditions

• Keep below 30°C temperature
• Protected from light & moisture
• Keep out of the reach of children

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