Terbikill 1% (Cream)

15 gm tube: ৳ 100.00

Medicine Details

Indications

  • Treatment of onychomycosis of the toenail
  • Treatment of onychomycosis of the fingernail
  • Treatment of Tinea Capitis
  • Treatment of fungal infection of the skin
  • Treatment of yeast infections of the skin
  • Treatment of Pityriasis (tinea) versicolor
  • Treatment of Tinea infections of the skin

Pharmacology

  • Inhibits biosynthesis of Ergosterol
  • Fungicidal against Tricophyton Mentagrophyte
  • Fungicidal against Trichophyton Rubrum
  • Increases membrane permeability

Dosage & Administration

  • Tablet dosage for fingernail onychomycosis
  • Tablet dosage for toenail onychomycosis
  • Granules dosage based on body weight
  • Cream application frequency
  • Duration of treatment for different infections
  • Spray application frequency

Interaction

  • Inhibitor of the CYP450 2D6 isozyme
  • May require reduction in dose of 2D6-metabolized drugs

Contraindications

  • Contra-indicated in individuals hypersensitive to terbinafine

Side Effects

  • Gastrointestinal symptoms
  • Liver test abnormalities
  • Rashes
  • Urticaria
  • Pruritus
  • Taste disturbances
  • Idiosyncratic and symptomatic hepatic injury
  • Liver failure
  • Serious skin reactions
  • Severe neutropenia
  • Thrombocytopenia
  • Angioedema
  • Allergic reactions
  • Malaise
  • Fatigue
  • Vomiting
  • Arthralgia
  • Myalgia
  • Hair loss

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Present in the breast milk of nursing mothers
  • Foetal toxicity and fertility studies in animals
  • Not recommended in nursing mothers

Precautions & Warnings

  • Cases of liver failure
  • Potential skin reactions
  • External use only
  • Not recommended for patients with chronic or active liver disease
  • Hepatotoxicity may occur

Use in Special Populations

  • Safety and efficacy not established in pediatric patients
  • No evidence to suggest different dosages or side-effects in elderly patients

Overdose Effects

  • Limited clinical experience with overdose
  • Doses up to 5 gm taken without serious adverse reactions
  • Symptoms of overdose include nausea, vomiting, abdominal pain, dizziness, rash

Therapeutic Class

  • Other Antifungal preparations
  • Topical Antifungal preparations

Storage Conditions

  • Store in a cool and dry place
  • Below 30°C
  • Protect from light

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