Terbikill 1% (Cream)
15 gm tube: ৳ 100.00
Medicine Details
Category | Details |
---|---|
Generic | Terbinafine hydrochloride |
Company | Acme laboratories ltd |
Also available as |
Indications
- Treatment of onychomycosis of the toenail
- Treatment of onychomycosis of the fingernail
- Treatment of Tinea Capitis
- Treatment of fungal infection of the skin
- Treatment of yeast infections of the skin
- Treatment of Pityriasis (tinea) versicolor
- Treatment of Tinea infections of the skin
Pharmacology
- Inhibits biosynthesis of Ergosterol
- Fungicidal against Tricophyton Mentagrophyte
- Fungicidal against Trichophyton Rubrum
- Increases membrane permeability
Dosage & Administration
- Tablet dosage for fingernail onychomycosis
- Tablet dosage for toenail onychomycosis
- Granules dosage based on body weight
- Cream application frequency
- Duration of treatment for different infections
- Spray application frequency
Interaction
- Inhibitor of the CYP450 2D6 isozyme
- May require reduction in dose of 2D6-metabolized drugs
Contraindications
- Contra-indicated in individuals hypersensitive to terbinafine
Side Effects
- Gastrointestinal symptoms
- Liver test abnormalities
- Rashes
- Urticaria
- Pruritus
- Taste disturbances
- Idiosyncratic and symptomatic hepatic injury
- Liver failure
- Serious skin reactions
- Severe neutropenia
- Thrombocytopenia
- Angioedema
- Allergic reactions
- Malaise
- Fatigue
- Vomiting
- Arthralgia
- Myalgia
- Hair loss
Pregnancy & Lactation
- Not recommended during pregnancy
- Present in the breast milk of nursing mothers
- Foetal toxicity and fertility studies in animals
- Not recommended in nursing mothers
Precautions & Warnings
- Cases of liver failure
- Potential skin reactions
- External use only
- Not recommended for patients with chronic or active liver disease
- Hepatotoxicity may occur
Use in Special Populations
- Safety and efficacy not established in pediatric patients
- No evidence to suggest different dosages or side-effects in elderly patients
Overdose Effects
- Limited clinical experience with overdose
- Doses up to 5 gm taken without serious adverse reactions
- Symptoms of overdose include nausea, vomiting, abdominal pain, dizziness, rash
Therapeutic Class
- Other Antifungal preparations
- Topical Antifungal preparations
Storage Conditions
- Store in a cool and dry place
- Below 30°C
- Protect from light