Gabatec 25 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It does not bind directly to GABA A, GABA B or benzodiazepine receptors. Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
Dosage
- Maximum recommended dose of Pregabalin: 100 mg three times a day (300 mg/day) for DPN
- Recommended dose of Pregabalin: 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day) for PHN
- Recommended dose of Pregabalin: 300 to 450 mg/day for fibromyalgia
- Recommended dose range of Pregabalin: 150 to 600 mg/day for spinal cord injury
Administration
- Route of administration: Oral
- Administration instructions: Swallow whole; should be administered after an evening meal
Interaction
- Drug interaction with medication: Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal
Pregnancy & Lactation
No adequate and well-controlled studies in pregnant women; Small amounts detected in the milk of lactating women
Precautions & Warnings
- Angioedema
- Hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Respiratory depression
- Dizziness and somnolence
- Increased seizure frequency with rapid discontinuation
- Peripheral edema
Use in Special Populations
Safety and effectiveness not established for pediatric patients and patients below the age of 1 month
Overdose Effects
Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- What is Gabatec 25 mg Capsule?
- How long do I need to use Gabatec 25 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Gabatec 25 mg Capsule?
- Should I use Gabatec 25 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Gabatec 25 mg Capsule?
- Does Gabatec 25 mg Capsule work in the same way for each disease?
- How long do I need to take Gabatec 25 mg Capsule?
- Is it necessary to continue taking Gabatec 25 mg Capsule even if I feel fine?
- Can I take Diazepam and Gabatec 25 mg Capsule together?
- Can the use of Gabatec 25 mg Capsule cause weight gain?
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