Glimitus 2 mg (Tablet)

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Glimepiride
Company Ziska pharmaceuticals ltd
Also available as
Glimitus 1 mg tablet Glimitus 3 mg tablet Glimitus 4 mg tablet

Title

Glimepiride Tablets

Categories

  • Antidiabetic Agent
  • Medication
  • Healthcare

Description

Glimepiride tablets are indicated as an adjunct to diet and exercise to lower the blood glucose in patients with noninsulin dependent (Type II) diabetes mellitus (NIDDM) whose hyperglycaemia cannot be controlled by diet and exercise alone. It may be used concomitantly with metformin when diet, exercise, and Glimepiride or metformin alone does not result in adequate glycaemic control. Glimepiride is also indicated for use in combination with insulin to lower blood glucose in patients whose hyperglycaemia cannot be controlled by diet and exercise in conjunction with an oral hypoglycaemic agent.

Attributes

  • Indications:
    • Adjunct to diet and exercise
    • Lower blood glucose
    • Noninsulin dependent diabetes mellitus
    • Concomitant use with metformin
    • Combination with insulin
  • Pharmacology:
    • Sulfonylurea antidiabetic agent
    • Decreases blood glucose concentration
    • Stimulates release of insulin
    • Improves sensitivity of beta cells to glucose stimulus
    • Reduction of basal hepatic glucose production
  • Dosage:
    • Based on desired blood sugar level
    • Lowest effective dose
    • Initial and maintenance doses based on regular glucose monitoring
    • Titration based on regular blood sugar monitoring
    • Dose range in patients with well controlled diabetes
    • Timing and distribution of doses determined by physician
    • Dose adjustment with changes in weight or lifestyle
  • Administration: Must be swallowed with sufficient amount of liquid
  • Interactions:
    • Potentiating drugs:
      • ACE inhibitors
      • Coumarin derivatives
      • Fluconazole
      • Quinolones
      • Sulphonpyrazone
    • Attenuating drugs:
      • Barbiturates
      • Corticosteroids
      • Glucagon
      • Laxatives
      • Rifampicin
    • Masking of symptoms:
      • Beta-receptor blockers
      • Clonidine
      • Guanethidine
    • Alcohol intake: May potentiate or attenuate the activity of Glimepiride
  • Contraindications:
    • Insulin dependent diabetes mellitus
    • Diabetic ketoacidosis
    • Diabetic coma
    • Hypersensitivity to Glimepiride
    • Severe hepatic dysfunction
    • Severe impairment of renal function
    • Dialysis patients
  • Side Effects:
    • Hypoglycaemia
    • Temporary visual impairment
    • Nausea
    • Vomiting
    • Diarrhoea
    • Abdominal pain
    • Urticaria
    • Fall in blood pressure
  • Pregnancy & Lactation:
    • Not suitable during pregnancy
    • Ingestion with breastfeeding may harm the child
    • Changeover to insulin necessary for pregnant patients
  • Precautions & Warnings:
    • Increased risk of hypoglycaemia in initial weeks of treatment
    • Prompt control of hypoglycaemia with immediate intake of carbohydrates
  • Overdose Effects:
    • Hypoglycaemia
    • Treatment with oral glucose and dosage adjustments
    • Severe cases require hospitalization and intravenous glucose injection
  • Therapeutic Class: Sulfonylureas
  • Storage Conditions: Store below 30°C, away from light, and out of the reach of children

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