Glimitus 4 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Indications

  • Adjunct to diet and exercise for Type II diabetes mellitus
  • Combination therapy with metformin
  • Combination therapy with insulin
  • Potential for hypoglycemia with combined use of Glimitus and insulin

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin

Dosage

  • Determined by desired blood sugar level
  • Initial dose of 1mg once daily
  • Dose titration based on regular blood sugar monitoring
  • Usual dose range in well controlled diabetes is 1 to 4 mg daily

Administration

Tablet must be swallowed with sufficient amount of liquid

Interactions

  • Potentiating drugs:
    • ACE inhibitors
    • Azapropazone
    • Cyclophosphamide
    • Fluconazole
    • Guanethidine
  • Attenuating drugs:
    • Barbiturates
    • Calcium channel blockers
    • Corticosteroids
    • Diazoxide
    • Diuretics

Contraindications

  • Not suitable for insulin-dependent diabetes mellitus
  • Hypersensitivity to Glimepiride
  • Severe hepatic dysfunction
  • Severe impairment of renal function
  • Dialysis patients

Side Effects

  • Hypoglycemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain

Pregnancy & Lactation

  • Not to be taken during pregnancy
  • Ingestion may harm breastfeeding child

Precautions & Warnings

Initial weeks require careful monitoring for increased risk of hypoglycemia

Overdose Effects

Can produce hypoglycemia, requiring aggressive treatment and close monitoring

Therapeutic Class

Sulfonylureas

Storage Conditions

Do not store above 30°C, keep away from light and out of the reach of children

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