Linera M 2.5 mg+500 mg (Tablet)
Unit Price: ৳ 12.00 (4 x 8: ৳ 384.00)
Strip Price: ৳ 96.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linagliptin metformin hydrochloride |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibitor of DPP-4 enzyme
- Increases active incretin hormones
- Stimulates insulin release
- Decreases glucagon secretion
- Oral antihyperglycemic drug
- Lowers plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage
- Maximum recommended dose
- Gradual dose escalation
- Immediate release tablet
- Extended release tablet
- Recommended starting dose
- Dose escalation for new and existing patients
- Switching from individual components to combination
Interaction
- Cationic drug interactions
- Carbonic anhydrase inhibitor interactions
- Inducers of P-glycoprotein and CYP3A4 enzymes
- Drugs affecting glycemic control
Contraindications
- Renal impairment
- Acute or chronic metabolic acidosis
- Hypersensitivity
Side Effects
- Nasopharyngitis
- Diarrhea
- Hypoglycemia
Pregnancy & Lactation
- Use only if clearly needed
- Caution during lactation
Precautions & Warnings
- Discontinue in lactic acidosis
- Discontinue in pancreatitis
- Discontinue during radiologic studies and surgical procedures
- Monitor Vitamin B12 levels
- Symptoms and precautions for lactic acidosis
- Precautions for alcohol, other medicines, counseling, travel, and emergencies
- Hypoglycemia symptoms and precautions
Overdose Effects
- Supportive measures for overdose
- Hemodialysis for Metformin Hydrochloride overdose
- No dose-related clinical adverse drug reactions for Linagliptin
- Hypoglycemia and lactic acidosis in Metformin Hydrochloride overdose
Therapeutic Class
- Oral hypoglycemic preparations
Storage Conditions
- Cool & dry place
- Below 30°C
- Protected from light & moisture
- Keep out of the reach of children