Merogit 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 700.00

Medicine Details

Category	Details
Generic	Meropenem trihydrate
Company	Ziska pharmaceuticals ltd
Also available as	Merogit 250 mg injection Merogit 1 gm injection

Indications

Pneumonia and Nosocomial Pneumonia
Urinary Tract Infections
Intra-abdominal Infections
Gynaecological Infections
Skin and Skin Structure Infections
Meningitis
Septicaemia
Pulmonary infections in cystic fibrosis
Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Carbapenem antibiotic for parenteral use with bactericidal action by interfering with bacterial cell wall synthesis

Dosage

500 mg to 1 gm by intravenous administration every 8 hours for adults
10 to 40 mg/kg intravenously every 8 hours for children

Administration

Intravenous infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes

Interaction

Competes with Probenecid, may reduce serum valproic acid levels

Contraindications

Hypersensitivity to the product

Side Effects

Inflammation
Thrombophlebitis
Pain at the site of injection
Skin reactions like rash, pruritus, urticaria
Abdominal pain
Nausea
Vomiting
Diarrhea
Headache

Pregnancy & Lactation

Category B in pregnancy, caution in nursing women

Precautions & Warnings

Discontinue if allergic reaction occurs
Use with careful monitoring in patients with hepatic disease

Use in Special Populations

Dosage reduction in renal impairment
No dosage adjustments in hepatic impairment
No dosage adjustments in elderly patients
Efficacy and tolerability not established in infants under 3 months

Overdose Effects

Symptomatic treatment, haemodialysis in renal impairment

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Intravenous bolus and infusion administration with compatible infusion fluids

Storage Conditions

Store in a cool, dry place below 30°C, away from light and moisture

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