Merogit 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category	Details
Generic	Meropenem trihydrate
Company	Ziska pharmaceuticals ltd
Also available as	Merogit 250 mg injection Merogit 500 mg injection

Indications

Treatment of pneumonia
Treatment of nosocomial pneumonia
Treatment of urinary tract infections
Treatment of intra-abdominal infections
Treatment of gynaecological infections
Treatment of skin and skin structure infections
Treatment of meningitis
Treatment of septicaemia
Treatment of pulmonary infections in cystic fibrosis
Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis

Dosage

Recommended daily dosage for adults
Usual dose for adults
Dosage for adults with pneumonia, urinary tract infections, gynaecological infections
Dosage for adults with nosocomial pneumonia, peritonitis, presumed infections in neutropenic patients and septicaemia
Dosage for adults with intra-abdominal infections
Dosage for adults with cystic fibrosis
Dosage for adults with meningitis
Dosage for children
Dosage for children with intra-abdominal infections
Dosage for children with cystic fibrosis
Dosage for children with meningitis
Dosage for children with febrile neutropenia
Dosage for children over 50 kg weight
No experience in children with hepatic or renal impairment

Administration

Intravenous infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes

Interaction

Competes with Probenecid for active tubular secretion
May reduce serum valproic acid levels

Contraindications

Hypersensitivity to the product

Side Effects

Inflammation
Thrombophlebitis
Pain at the site of injection
Skin reactions like rash, pruritus, urticaria
Abdominal pain
Nausea
Vomiting
Diarrhea
Headache

Pregnancy & Lactation

Category B; Caution during pregnancy and lactation

Precautions & Warnings

Discontinue if allergic reaction occurs, use with careful monitoring in patients with hepatic disease

Use in Special Populations

Dosage reduction in patients with creatinine clearance less than 51 ml/min
No dosage adjustments for hepatic impairment
Elderly patients dosage adjustments if creatinine clearance is <51 ml/min
Efficacy and tolerability not established in infants under 3 months

Overdose Effects

Accidental overdose could occur; treatment should be symptomatic

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Preparation of solution for intravenous bolus Administration and intravenous infusion administration; Compatible with various infusion fluids; Freshly reconstituted solution is recommended

Storage Conditions

Store below 30°C, away from light & moisture, Keep out of the reach of children