L-Cardin 4 mg (Tablet)

Unit Price: ৳ 5.05 (3 x 10: ৳ 151.50)
Strip Price: ৳ 50.50

Medicine Details

Category Details
Generic Lacidipine
Company Drug international ltd
Also available as
L cardin 2 mg tablet

Indications

  • Treatment of hypertension
  • Can be used alone or in combination with other antihypertensive agents

Pharmacology

  • Inhibits influx of calcium into smooth muscle cells
  • Competitive inhibition of voltage-dependent calcium 'L' channels

Dosage & Administration

  • Recommended initial dose of 2 mg once daily
  • Dose may be increased to 4 mg and then to 6 mg after 3 to 4 weeks
  • Preferred to be taken in the morning

Interaction

  • Possible increase in plasma concentration by cimetidine
  • No identified pharmacodynamic interactions with common antihypertensive agents or with digoxin, tolbutamide, or warfarin

Contraindications

  • Hypersensitivity to any ingredient
  • Cardiogenic shock
  • Unstable angina
  • Aortic stenosis
  • Avoid within 1 month of myocardial infarction
  • Impaired left ventricular function

Side Effects

  • Flushing
  • Palpitation
  • Edema
  • Headache
  • Dizziness
  • Gastro-intestinal disturbances
  • Gum hyperplasia
  • Mood disturbances
  • Asthenia
  • Polyuria
  • Muscle cramps
  • Skin rash

Pregnancy & Lactation

  • No data on safety in human pregnancy
  • No evidence of teratogenic effect in animal study
  • Likely excretion into breast milk
  • Should not be used during pregnancy or lactation

Precautions & Warnings

  • Cardiac conduction abnormalities
  • Poor cardiac reserves
  • Hepatic impairment
  • Withdraw if ischemic pain occurs shortly after initiating treatment or if cardiogenic shock develops
  • Avoid grapefruit juice

Use in Special Populations

  • No data on safety or efficacy in neonates
  • Treatment not evaluated in children
  • Severe hepatic impairment: Reduce dose

Overdose Effects

  • Prolonged peripheral vasodilation associated with hypotension and tachycardia
  • Bradycardia or prolonged AV conduction
  • Symptomatic and supportive treatment for management

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Store in a cool and dry place
  • Protect from light and moisture
  • Keep out of the reach of children

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