Fenatrol 200 mg (Capsule)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)

Strip Price: ৳ 70.00

Medicine Details

Fenatrol is indicated for hyperlipidemias of type lla, llb, III, IV & V in patients who have not responded adequately to diet & other appropriate measures.

Fenofibrate is a fibric acid derivative.
Fenofibrate is rapidly hydrolyzed after oral ingestion to its pharmacologically active form, fenofibric acid.
Fenofibric acid produces reductions in total cholesterol, LDL cholesterol, Apo-lipoprotein B, Total triglycerides and VLDL.
Treatment with Fenofibrate results in increases in HDL and apo-proteins apoAI apoAII.
Fenofibrate reduces serum uric acid levels in hyperuricemic and normal individuals by increasing the urinary excretion of uric acid.
The micronised form of Nofiate (Fenofibrate) has enhanced absorption over the non-micronised formulation.

For the treatment of adult patients with hypercholesterolemia or mixed hyperlipidemia, the initial dose of Fenofibrate is 200 mg per day.
For adult patients with hypertriglyceridemia, the initial dose is 67 to 200 mg per day.
Dose should be individualized according to patient response.
Fenofibrate should be given with meal to optimize the bioavailability of the medication. Or, as directed by the registered physician.

Fenatrol has been reported to potentiate the anticoagulant effects of warfarin.
When administered with antidiabetic drug it may improve glucose tolerance and have additive effect.
Fenatrol may also increase the nephrotoxicity of cyclosporine.
Cautions should be taken against the use of Fenatrol with HMG-CoA reductase inhibitors.
The use of low-dose statins with Fenatrol appears to be well tolerated.

Fenofibrate is contraindicated in patients with hypersensitivity to Fenofibrate.
It is contraindicated in severe renal or hepatic impairment.
Contraindicated in patients with existing gall bladder disease, breast feeding mothers, and those with photosensitivity to ketoprofen.

Gastro-intestinal issues like nausea, anorexia, and gastric pain.
Pruritus, urticaria, impotence, headache, dizziness, vertigo, fatigue, hair loss.
Myotoxicity is also a potential side effect.

Special care needed in patients with renal disease, as progressive increases in serum creatinine concentration or failure to follow dosage guidelines may result in myotoxicity.
Discontinue if myotoxicity is suspected or if creatinine kinase concentration increases significantly.
Liver function tests recommended every 3 months for the first year.

There is no specific treatment for overdose with Fenatrol.
General supportive care of the patients is indicated, including monitoring of vital signs and observation of clinical status, should an overdose occur.
Hemodialysis should not be considered as Fenatrol is highly bound to plasma proteins.