Hydrason 20 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Hydrocortisone |
| Company | Drug international ltd |
| Also available as |
Indications
- Primary or secondary adrenocortical insufficiency
- Acute adrenocortical insufficiency
- Shock unresponsive to conventional therapy
- Congenital adrenal hyperplasia
- Hypercalcemia associated with cancer
- Nonsuppurative thyroiditis
- Rheumatic Disorders
- Dermatologic Diseases
- Control of severe or incapacitating allergic conditions
- Ophthalmic Diseases
- Gastrointestinal Diseases
- Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy
- Loeffler's syndrome
- Aspiration pneumonitis
- Hematologic Disorders
- Neoplastic Diseases
- Edematous States
- Acute exacerbations of multiple sclerosis
Pharmacology
Hydrocortisone inhibits prostaglandin synthesis, reduces vasoactive agents released during inflammation, and controls the rate of protein synthesis.
Dosage & Administration
- Initial dosage may vary from 20 mg to 240 mg of hydrocortisone per day
- Dosage requirements are variable and must be individualized
- Injection for adults and children at specific doses
Interaction
Drugs that induce hepatic enzymes or inhibit corticosteroid metabolism may affect corticosteroid clearance and require dose adjustments to avoid toxicity.
Contraindications
Contraindicated in severe systemic fungal infections and known hypersensitivity to any component of the product.
Side Effects
Generally well tolerated except in prolonged high doses, potential side effects include cardiac arrhythmia, esophageal candidiasis, menstrual irregularity, decreased carbohydrate & glucose tolerance, fluid retention, increased appetite, weight gain, euphoria, mood swings, depression, insomnia, acne, etc.
Pregnancy & Lactation
To be prescribed in pregnancy and lactation only if absolutely required.
Precautions & Warnings
Use with caution in patients with a history of peptic ulceration, congestive heart failure, hypertension, glaucoma, diabetes, and epilepsy.
Therapeutic Class
Glucocorticoids
Storage Conditions
Store below 30°C temperature, away from light & moisture, and out of the reach of children.