Tamlet 0.4 mg (Capsule (Modified Release))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Tamsulosin hydrochloride
Company Sun pharmaceutical bangladesh ltd

Indications

  • Treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)

Pharmacology

  • Selective alpha1 adrenoceptor blocking agent
  • Improvement in urine flow rate
  • Reduction in symptoms of BPH
  • Absorption rate under fasting and fed conditions
  • Plasma protein binding
  • Metabolism by cytochrome P 450 enzymes
  • Elimination half-life
  • Apparent half-life in healthy volunteers and target population

Dosage & Administration

  • 0.4 mg (one capsule) daily
  • Possible dose increase after 2 to 4 weeks
  • Administration after meal at night
  • Recommendation for swallowing whole with water
  • Instructions on not crushing or chewing the capsule

Interaction

  • Potential hypotensive effects of concurrent alfa1-adrenoceptor antagonists
  • No interactions with atenolol, enalapril, or nifedipine
  • Impact of cimetidine and frusemide on plasma levels
  • No interactions at the level of hepatic metabolism observed during in vitro studies
  • Possible increase in elimination rate with diclofenac and warfarin

Contraindications

  • Hypersensitivity to Tamsulosin hydrochloride
  • History of orthostatic hypotension
  • Severe hepatic insufficiency
  • Caution advised for reduction in blood pressure
  • Examination to exclude other conditions
  • Caution in driving, operating machinery, or performing hazardous tasks

Side Effects

  • Reported adverse reactions: dizziness, abnormal ejaculation
  • Less frequent adverse reactions: headache, asthenia, postural hypotension, palpitations

Pregnancy & Lactation

  • Not recommended for use in pregnancy and lactation

Precautions & Warnings

  • Rare occurrence of transient postural symptoms
  • Caution advised for patients with micturition syncope
  • Unknown effects on ability to drive or operate machines
  • Patient awareness of potential dizziness

Overdose Effects

  • No reported case of acute overdosage
  • Likelihood of acute hypotension after overdosage
  • Recommended cardiovascular support and monitoring of renal function
  • Potential measures to impede absorption

Therapeutic Class

  • BPH/ Urinary retention/ Urinary incontinence

Storage Conditions

  • Cool and dry place
  • Below 30°C
  • Protection from light

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