Telpro 40 mg (Tablet)
Unit Price: ৳ 12.50 (2 x 10: ৳ 250.00)
Strip Price: ৳ 125.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Telmisartan |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of essential hypertension in adults
- Reduction of cardiovascular morbidity in adults with atherothrombotic cardiovascular disease
- Reduction of cardiovascular morbidity in adults with type 2 diabetes mellitus and documented target organ damage
Pharmacology
- Telmisartan is a non-peptide angiotensin-II receptor antagonist
- Blocks the vasoconstrictor and aldosterone secreting effects of angiotensin-II
- Greater affinity for the AT1 receptor than for the AT2 receptor
- Does not affect the response to bradykinin
Dosage & Administration
- Usual starting dose of 40 mg once a day
- Blood pressure response is dose-related over the range of 20 to 80 mg
- Most antihypertensive effect is apparent within 2 weeks
- Maximal reduction is generally attained after 4 weeks
- No initial dosage adjustment is necessary for elderly patients or patients with renal impairment
- May be administered with or without food
Interaction
- Increased risk of renal impairment and loss of antihypertensive effect with NSAIDs
- Co-administration with aliskiren in patients with diabetes should be avoided
Contraindications
- Known hypersensitivity to this product or any of its components
Side Effects
- Common side effects in hypertensive patients include sinus pain, congestion, back pain, and diarrhea
- Common side effects in patients of cardiovascular risk reduction include intermittent claudication and skin ulcer
Pregnancy & Lactation
- Pregnancy Category C (first trimester) and D (second and third trimester)
- Potential adverse effects on the nursing infant
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Monitor carefully in patients with impaired hepatic or renal function
- Avoid concomitant use of an ACE inhibitor and angiotensin receptor blocker
Overdose Effects
- Manifestations of overdosage may include hypotension, dizziness, tachycardia, bradycardia, increase in serum creatinine, and acute renal failure
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children