Telpro Max 5 mg+80 mg (Tablet)

Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Amlodipine besilate telmisartan
Company Renata limited
Also available as

Indications

  • Treatment of hypertension
  • Treatment with other antihypertensive agents
  • Initial therapy for patients needing multiple drugs to achieve blood pressure goals

Pharmacology

  • Combination of Telmisartan and Amiodipine
  • Mechanism of action on angiotensin II and calcium channels
  • Effects on renin-angiotensin system
  • Blood pressure reduction
  • Selective binding to AT1 receptor
  • Vasodilation
  • Peripheral vascular resistance reduction

Dosage & Administration

  • Usual starting dose of 40/5mg once daily
  • Larger blood pressure reductions with 80/5mg once daily
  • Patients requiring additional blood pressure reduction
  • Individualized dosage
  • Maximum recommended dose of 80/10mg once daily

Interaction

  • No clinically significant interaction with acetaminophen, glyburide, simvastatin, hydrochlorothiazide, warfarin, ibuprofen
  • Inhibition of CYP2C19

Contraindications

  • Known hypersensitivity to the product or its components
  • Pregnancy & lactation
  • Biliary obstructive disorders
  • Severe hepatic impairment
  • Hypotension
  • Cardiogenic shock
  • Left ventricle outflow tract obstruction

Side Effects

  • Dizziness
  • Peripheral edema
  • Migraine
  • Headache
  • Paraesthesia
  • Bradycardia
  • Palpitations
  • Hypotension
  • Cough
  • Abdominal pain
  • Diarrhea
  • Nausea
  • Pruritus
  • Myalgia
  • Spasm
  • Erectile dysfunction
  • Chest pain
  • Fatigue

Pregnancy & Lactation

  • Pregnancy Categories C and D
  • Potential adverse effects on nursing infant
  • Discontinuation of nursing
  • Consideration of drug importance to the mother

Precautions & Warnings

  • Avoid fetal or neonatal exposure
  • Correct volume or salt depletion before initiating therapy
  • Titration in patients with hepatic or severe renal impairment
  • Monitoring for worsening heart failure
  • Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
  • Risk of myocardial infarction in patients with severe obstructive coronary artery disease

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • Initial therapy not recommended in patients ≥75 years old
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • Manifestations of overdosage
  • Supportive treatment for symptomatic hypotension
  • Cardiac and respiratory monitoring
  • Frequent blood pressure measurements
  • Vasopressors administration if hypotension remains unresponsive
  • Not removed by hemodialysis

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Protection from light and high humidity
  • Keep out of the reach of children

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