Telpro Max 5 mg+80 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of hypertension
- Treatment with other antihypertensive agents
- Initial therapy for patients needing multiple drugs to achieve blood pressure goals
Pharmacology
- Combination of Telmisartan and Amiodipine
- Mechanism of action on angiotensin II and calcium channels
- Effects on renin-angiotensin system
- Blood pressure reduction
- Selective binding to AT1 receptor
- Vasodilation
- Peripheral vascular resistance reduction
Dosage & Administration
- Usual starting dose of 40/5mg once daily
- Larger blood pressure reductions with 80/5mg once daily
- Patients requiring additional blood pressure reduction
- Individualized dosage
- Maximum recommended dose of 80/10mg once daily
Interaction
- No clinically significant interaction with acetaminophen, glyburide, simvastatin, hydrochlorothiazide, warfarin, ibuprofen
- Inhibition of CYP2C19
Contraindications
- Known hypersensitivity to the product or its components
- Pregnancy & lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Hypotension
- Cardiogenic shock
- Left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Headache
- Paraesthesia
- Bradycardia
- Palpitations
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Pruritus
- Myalgia
- Spasm
- Erectile dysfunction
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Potential adverse effects on nursing infant
- Discontinuation of nursing
- Consideration of drug importance to the mother
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion before initiating therapy
- Titration in patients with hepatic or severe renal impairment
- Monitoring for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
- Risk of myocardial infarction in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Initial therapy not recommended in patients ≥75 years old
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- Manifestations of overdosage
- Supportive treatment for symptomatic hypotension
- Cardiac and respiratory monitoring
- Frequent blood pressure measurements
- Vasopressors administration if hypotension remains unresponsive
- Not removed by hemodialysis
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protection from light and high humidity
- Keep out of the reach of children