Voritec 200 mg (Tablet)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by certain fungal species
- Intolerance or refractory to other therapy
Pharmacology
- Voriconazole is a triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
- Depletes ergosterol in fungal cell membrane
Dosage & Administration
- Oral tablet and powder for suspension
- Different loading and maintenance doses based on body weight
- Specific dosage for different fungal infections
- Injection dosage for invasive aspergillosis, candidemia, Scedosporiosis and Fusariosis
Interaction
- Adjust dosage and monitor for adverse reactions with CYP inhibitors and inducers
- May increase concentrations and activity of CYP substrates
- Increase maintenance dosage with co-administration of specific drugs
Contraindications
- Known hypersensitivity to Voriconazole
- Co-administration with specific drugs due to risk of serious adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Use during pregnancy only if potential benefit justifies potential risk to fetus
Precautions & Warnings
- Careful assessment of benefit-risk balance for long term exposure
- Reported association with squamous cell carcinoma of the skin (SCC)
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No data available
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Shake powder well before adding water
- Specific reconstitution instructions for suspension
- Discard suspension 14 days after reconstitution
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C temperature and protected from light
- Store powder for suspension between 2° to 8°C temperature