Angimil SR 240 mg (Tablet)
Unit Price: ৳ 7.00 (15's pack: ৳ 105.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Verapamil hydrochloride |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Title
- Angimil SR Tablet
- Angimil SR Injection
Categories
- Medicine
- Healthcare
- Pharmaceutical
Description
- Calcium ion influx inhibitor
- Sustained release formulation
- Inhibits inward movement of calcium into cells
Color Options
- None
Functions
- Antiarrhythmic
- Antianginal
- Antihypertensive
Materials
- Verapamil hydrochloride
Technical Specifications
- L-type calcium channel blocker
- Extended-release formulations available
- Once-daily dosing
Design Elements
- Tablet
- Injection
Usability Features
- Individualized dosage by titration
- Administered with food
- Various dosage regimens for different conditions
- Intravenous administration in adults and children
Pharmacology
- Negative inotropic medication
- Inhibits inward movement of calcium
- Short duration of action for immediate-release form
Dosage & Administration
- Individualized by titration
- Different initial doses for essential hypertension and arrhythmias
- Intravenous administration for tachycardias and hypertensive crises
Interaction
- May increase plasma level with CYP3A4 inhibitors
- May decrease plasma level with CYP3A4 inducers
- Increased risk of bleeding with aspirin
- Potentiates hypotensive effect with diuretics and vasodilators
Contraindications
- Severe left ventricular dysfunction
- Hypotension or cardiogenic shock
- Sick sinus syndrome
- Second or third-degree atrioventricular block
- Known hypersensitivity
Side Effects
- Constipation
- Nausea
- Hypotension
- Edema
- CHF
- Pulmonary edema
- Bradycardia
- Rash
- Elevated liver enzyme
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Excretion in breast milk
Precautions & Warnings
- Care required in 1st degree AV block, bradycardia, hypotension
- May impair ability to drive or operate machinery
- Slows down the elimination of alcohol
Overdose Effects
- Supportive treatment
- Beta-adrenergic stimulation to increase calcium ion flux
- Cannot be removed by hemodialysis
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children