Varox 10 mg (Tablet)

Unit Price: ৳ 25.00 (1 x 14: ৳ 350.00)

Strip Price: ৳ 350.00

Medicine Details

Category	Details
Generic	Rivaroxaban
Company	Drug international ltd
Also available as	Varox 25 mg tablet

Indications

Prevention of atherothrombotic events after Acute Coronary Syndrome
Reduction of stroke and systemic embolism in nonvalvular atrial fibrillation
Treatment and prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE)
Prophylaxis of DVT in patients undergoing knee or hip replacement surgery

Pharmacology

Highly selective direct factor Xa inhibitor
Interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade
Does not inhibit thrombin
No effects on platelets

Dosage & Administration

Recommended dosage for different conditions
Variety of dosing options based on patient's condition and creatinine clearance
May be taken with or without food

Interaction

Concomitant use with drugs affecting P-gp and CYP3A4 inhibitors
Contraindicated with strong CYP3A4 inducers
Increased risk of bleeding with concomitant use of certain drugs

Contraindications

Known hypersensitivity to Rivaroxaban or its excipients
Active pathological bleeding

Side Effects

Increased chance of bleeding
Spinal or epidural hematoma
Increased risk of stroke after discontinuation in nonvalvular atrial fibrillation

Pregnancy & Lactation

Pregnancy category C drug
No established dosing for pregnant women
Unknown excretion in human milk
Safety and efficacy not established in breastfeeding women

Precautions & Warnings

Increased risk of thrombotic events with early discontinuation
Risk of fatal bleeding in the presence of certain risk factors
Monitoring of neurological impairment in cases of neuraxial anesthesia
Not recommended in certain patient populations

Overdose Effects

May lead to hemorrhage
Limited systemic exposure at single doses >50 mg
No specific antidote available

Therapeutic Class

Oral Anti-coagulants

Storage Conditions

Store below 30°C, protected from light

Related Brands