Tazumab 440 mg/20 ml (IV Infusion)
440 mg vial: ৳ 80,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Trastuzumab |
| Company | Drug international ltd |
Indications
- Adjuvant treatment of HER2 overexpressing breast cancer
- Treatment of metastatic breast cancer
- Treatment of metastatic gastric cancer
Pharmacology
- Inhibition of HER2 overexpressing tumor cell proliferation
- Mediator of antibody-dependent cellular cytotoxicity (ADCC)
Dosage
- Administration according to recommended doses and schedules
- Different dose regimens for adjuvant and metastatic treatment
Administration
- Reconstitution of lyophilized powder with diluent
- Proper storage and handling protocols
Interaction
- Increased risk of cardiac dysfunction with anthracycline therapy
- Recommendation to monitor patient's cardiac function carefully
Side Effects
- Serious adverse reactions including cardiomyopathy and infusion reactions
- Common adverse reactions such as fever, nausea, and vomiting
Pregnancy & Lactation
- Potential fetal harm when administered to pregnant women
- Recommendation for effective contraception during treatment and for 7 months following the last dose
Precautions & Warnings
- Risk of cardiac dysfunction and decline in left ventricular ejection fraction
- Thorough cardiac monitoring and assessment
- Management of infusion reactions and embryo-fetal toxicity
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
Reconstitution
- Instructions for reconstituting the lyophilized powder with specific diluents
Storage Conditions
- Proper storage requirements including temperature range and protection from light