Rivaren 1.5 mg (Capsule)
Unit Price: ৳ 20.00 (3 x 6: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivastigmine tartrate |
| Company | Renata limited |
| Also available as |
Indications
- Symptomatic treatment of mild to moderately severe Alzheimer's dementia
- Symptomatic treatment of mild to moderately severe dementia in patients with Idiopathic Parkinson's disease
Pharmacology
- Structurally related to physostigmine
- Binds reversibly with and inactivates cholinesterase
- Increases concentration of acetylcholine at cholinergic synapses
- Relatively specific for brain acetylcholinesterase and butyrylcholinesterase
Dosage
- Rivastigmine capsule initial dose of 1.5 mg twice a day
- Dosage titration starting with 1.5 mg twice a day and may be increased to 3 mg, 4.5 mg, and then 6 mg twice a day
- Recommended maximum daily dose is 6 mg twice a day for maintenance treatment
- Rivastigmine transdermal patch dosage of 4.6 mg/24 hours as an initial dose
Administration
- Administered twice a day, with morning and evening meals
Interaction
- Exaggerates the effects of succinylcholine-type muscle relaxants
- Caution with anaesthetic agents
- Should not be given concomitantly with other cholinomimetic substances
Contraindications
- Contraindicated in patients with hypersensitivity to the active substance or other carbamate derivatives
Side Effects
- Commonly reported gastrointestinal adverse reactions like nausea and vomiting
Pregnancy & Lactation
- Not recommended during pregnancy
- Not recommended for breastfeeding women
Precautions & Warnings
- Caution for patients with sick sinus syndrome or conduction defects
- Cholinergic stimulation may increase gastric acid secretion
- May worsen extrapyramidal symptoms
- Monitor body weight in patients
Use in Special Populations
- Increased exposure in moderate renal and mild to moderate hepatic impairment
- Not recommended for use in children
Overdose Effects
- Accidental overdose may lead to symptoms like nausea, vomiting, diarrhoea, hypertension, and hallucinations
- Vagotonic effect of cholinesterase inhibitors may cause bradycardia and/or syncope
Therapeutic Class
- Drugs for Dementia
Storage Conditions
- Store in a cool and dry place, protected from light