Telpro Max 5 mg+40 mg (Tablet)
Unit Price: ৳ 12.50 (2 x 10: ৳ 250.00)
Strip Price: ৳ 125.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of hypertension
- Combination therapy for blood pressure control
Pharmacology
- Contains Telmisartan and Amiodipine
- Action on angiotensin receptor
- Inhibition of calcium ion influx
- Vasodilator effect
- Reduction in peripheral vascular resistance
- No effect on pulse rate
Dosage & Administration
- Initial dose of 40/5 mg once daily
- 80/5 mg once daily for larger blood pressure reductions
- Add-on therapy for patients not adequately controlled with individual components
- Replacement therapy for patients already on separate Telmisartan and Amiodipine tablets
- Maximum recommended dose of 80/10 mg once daily
Interaction
- No clinically significant interaction with specific drugs
- No inhibition or metabolism effects on cytochrome P450 enzymes
Contraindications
- Hypersensitivity to the product or components
- Pregnancy & lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Hypotension
- Cardiogenic shock
- Left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Headache
- Paraesthesia
- Vertigo
- Bradycardia
- Palpitations
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Pruritus
- Myalgia
- Spasm
- Erectile dysfunction
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Potential excretion in human milk
- Recommendation to discontinue nursing or drug after considering importance to the mother
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion before therapy
- Monitor for signs of hypotension
- Slow titration in hepatic or severe renal impairment cases
- Monitor for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
- Potential risk in initiating CCB in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- Not recommended in patients ≥75 years old
- Not recommended in hepatically impaired patients
Overdose Effects
- Manifestations of over dosage with telmisartan - hypotension, dizziness, tachycardia
- Manifestations of over dosage with amiodipine - excessive peripheral vasodilation, marked hypotension, possibly reflex tachycardia
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children