Picaso 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sodium picosulfate |
| Company | Sharif pharmaceuticals ltd |
| Also available as |
Title
Picaso 10 mg Tablet
Categories
- Medicine
- Healthcare
- Pharmaceuticals
Description
Picaso 10 mg Tablet is indicated for constipation, relief from prolonged & recurrent constipation, and bowel clearance before surgery, childbirth or radiological investigations. It is a sodium picosulfate derivative stimulant laxative that acts locally in the colon, promoting accumulation of water and electrolytes, resulting in colonic peristalsis, reduction of transit time, and softening of the stool. The recommended dosages for adults and children vary based on the form of the medication (tablet, oral solution, concentrated oral solution). Contraindications include ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions, acute inflammatory bowel diseases, severe dehydration, and known hypersensitivity to sodium picosulfate. Side effects may include hypersensitivity, dizziness, syncope, gastrointestinal disorders, diarrhea, abdominal pain, and nausea. Precautions should be taken for prolonged excessive use, alcoholism, pregnancy, breastfeeding, children, and high-risk groups such as patients with liver disease or epilepsy. Storage conditions require keeping the product below 30°C temperature, away from light & moisture, and out of the reach of children. The chemical structure has a molecular formula of C18H15NNa2O9S2. It belongs to the therapeutic class of stimulant laxatives.
Attributes
- Indications:
- Constipation of any etiology
- Relief from prolonged & recurrent constipation
- Bowel clearance before surgery, childbirth or radiological investigations
- Pharmacology:
- Sodium Picosulfate is a triarylmethane group derivative stimulant laxative
- Activated by colonic bacteria
- Acts locally in the colon
- Stimulates nerve endings of the intestinal wall
- Promotes accumulation of water and electrolytes in the colonic lumen
- Results in colonic peristalsis
- Reduction of transit time and softening of the stool
- Stimulation of the rectum causes increased motility and a feeling of rectal fullness
- Dosage & Administration:
- For oral administration
- Recommended to be taken at night to produce evacuation the following morning
- Start with the lowest dose
- Dose may be adjusted up to the maximum recommended dose
- Maximum recommended daily dose should not be exceeded
- Interaction:
- The concomitant use of diuretics or adreno-corticosteroids may increase the risk of electrolyte imbalance if excessive doses are taken
- Concurrent administration of antibiotics may reduce the laxative action of Picaso
- Contraindications:
- Ileus or intestinal obstruction
- Severe painful and/or feverish acute abdominal conditions
- Acute inflammatory bowel diseases
- Severe dehydration
- Known hypersensitivity to Sodium Picosulfate or any other component of the product
- Side Effects:
- Hypersensitivity
- Dizziness
- Syncope
- Gastrointestinal disorders
- Diarrhea
- Abdominal pain
- Abdominal cramps
- Nausea
- Vomiting
- Pregnancy & Lactation:
- Use of the drug should be avoided during the first trimester
- Neither the active moiety of sodium Picosulfate nor its glucuronides are excreted into the milk of healthy lactating females
- Precautions & Warnings:
- Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia
- Harmful for those suffering from alcoholism
- To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease or epilepsy
- Overdose Effects:
- Chronic diarrhea
- Abdominal pain
- Hypokalemia
- Secondary hyperaldosteronism
- Renal calculi
- Renal tubular damage
- Metabolic alkalosis
- Muscle weakness secondary to hypokalemia
- Therapeutic Class: Stimulant Laxative
- Storage Conditions: Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children
- Chemical Structure:
- Molecular Formula : C18H15NNa2O9S2
- Common Questions:
- What is Picaso 10 mg Tablet?
- What are the uses of the Picaso 10 mg Tablet?
- How long do I need to use Picaso 10 mg Tablet before I see improvement in my condition?
- At what frequency do I need to use Picaso 10 mg Tablet?
- Should I use Picaso 10 mg Tablet empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Picaso 10 mg Tablet?
- Is Picaso 10 mg Tablet safe for pregnant women?
- Is Picaso 10 mg Tablet safe for breastfeeding women?
- Is Picaso 10 mg Tablet a habit forming drug?
- What if I miss a dose of Picaso 10 mg Tablet?
- Quick Tips - Take a fiber-rich diet, Avoid taking for more than 1 week, Take 2 hours apart from other medicines, Take at bedtime