Parkinor 100 mg+10 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Indications

  • Treatment of Parkinson's disease
  • Relief of parkinsonism symptoms
  • Management of tremor
  • Management of dysphagia
  • Management of sialorrhea
  • Postural instability management
  • Improves motor recovery after stroke

Description

  • Levodopa is metabolic precursor of dopamine
  • Carbidopa is a dopa decarboxylase inhibitor

Dosage & Administration

  • Dosage initiation guidelines
  • Titration guidelines for different tablet strengths
  • Maintenance dose guidelines

Interaction

  • Interaction with antihypertensive medications
  • Interaction with tricyclic antidepressants
  • Interaction with ferrous sulphate or ferrous gluconate
  • Interaction with dopamine-2 receptor antagonists
  • Interaction with isoniazid
  • Interaction with phenytoin and papaverine
  • Interaction with selegiline

Contraindications

  • Contraindicated in patients with hypersensitivity to Carbidopa and Levodopa
  • Contraindicated in patients with narrow-angle glaucoma
  • Not recommended in patients with suspicious undiagnosed skin lesions or a history of melanoma

Side Effects

  • Dyskinesias including choreiform, dystonic, and other involuntary movements
  • Nausea
  • Syncope
  • Chest pain
  • Anorexia
  • Palpitation
  • Orthostatic effects including hypotensive episodes
  • Hypertension
  • Phlebitis
  • Vomiting
  • Gastrointestinal bleeding
  • Development of duodenal ulcer
  • Diarrhoea
  • Dark saliva
  • Leukopenia
  • Haemolytic and non-haemolytic anaemia
  • Thrombocytopenia
  • Agranulocytosis
  • Angioedema
  • Urticaria
  • Pruritus
  • Henoch-Schonlein purpura
  • Dizziness
  • Somnolence
  • Paresthesia
  • Delusions
  • Hallucinations
  • Paranoid ideation
  • Depression with or without development of suicidal tendencies
  • Dementia
  • Dream abnormalities
  • Agitation
  • Confusion
  • Increased libido
  • Dyspnea
  • Alopecia
  • Rash
  • Dark sweat
  • Dark urine

Pregnancy & Lactation

  • Effects on human pregnancy are unknown
  • Potential hazards to pregnancy
  • Use in women of childbearing potential should be weighed against possible benefits
  • Unknown excretion in human milk
  • Consideration for nursing mothers

Precautions & Warnings

  • Not recommended for the treatment of medicine-induced extrapyramidal reactions
  • Caution in patients already taking Levodopa alone
  • Observation for depression and suicidal tendencies
  • Treatment caution for patients with past or current psychoses
  • Caution in patients with severe cardiovascular or pulmonary disease
  • Monitoring cardiac function
  • Careful management in chronic wide-angle glaucoma patients
  • Careful care in patients with a history of myocardial infarction
  • Monitoring intraocular pressure in chronic wide-angle glaucoma patients
  • Advised for patients with atrial, nodal, or ventricular arrhythmias

Use in Special Populations

  • Not established in infants and children below 18 years of age

Therapeutic Class

  • Antiparkinson drugs

Storage Conditions

  • Store in a cool and dry place
  • Protected from light

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