Clonepam 0.5 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Pacific pharmaceuticals ltd |
Indications
- Treatment of panic disorder with or without agoraphobia
- Adjunct in the treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Treatment of absence seizures (petit mal)
- Long-term use not systematically studied
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Modulation of GABA receptor affinity
- Effect on serotonin
- Suppression of paroxysmal activity
- Beneficial effects in generalized and focal epilepsies
Dosage & Administration
- Initial dose for adults with seizure disorders
- Maximum recommended daily dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosage for infants and children
- Dosage for adults via injection
Interaction
- Effect on the metabolism of phenytoin, carbamazepine, and phenobarbital
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Tremor
- Vertigo
- Depression
- Insomnia
- Increased libido
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential for congenital malformations
- Evidence of anticonvulsant drugs acting as teratogens
- Administration only if potential benefits outweigh the risk to the fetus
- Adverse effects on the newborn if administered in high doses during the last trimester or labor
- Passage into maternal milk in small amounts
Precautions & Warnings
- Potential to precipitate the onset of generalized tonic-clonic seizures
- Concomitant use with valproic acid
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- Effects on patients with renal impairment
- Effects on patients with hepatic impairment
Use in Special Populations
- Caution in maintaining patency of the airways in infants and small children
- Greater effects in elderly patients
- No dose adjustment required in patients with renal impairment
- Differences in plasma protein binding in cirrhotic patients
Overdose Effects
- Symptoms including drowsiness, ataxia, dysarthria, and nystagmus
- Life-threatening effects if taken with other central nervous system depressants
- Treatment involving monitoring vital signs and supportive measures
- Prevention of further absorption using activated charcoal
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Dilution with water for injection prior to administration
- Continuous monitoring of EEG, respiration, and blood pressure during IV injection
- Dilution for infusion in specific ratios with certain diluting media
- Precautions for intramuscular injection
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
Common Questions about Clonepam 0.5 mg Tablet
- Usage not as a sleeping pill
- Advised duration of use
- Withdrawal symptoms after stopping
- Monitoring for early symptoms of suicidal thoughts and actions
- Potential impact on weight and memory
- Harmful effects of overdose
- Drug interactions with zolpidem and quetiapine
- Quick tips for usage