Alphalok 2 mg (Tablet)

Unit Price: ৳ 6.00 (3 x 14: ৳ 252.00)
Strip Price: ৳ 84.00

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Opsonin pharma ltd
Also available as
Alphalok 1 mg tablet Alphalok xr 25 mg tablet Alphalok xr 5 mg tablet

Indications

  • Treatment of essential hypertension
  • Treatment of secondary hypertension
  • Treatment of left ventricular failure
  • Treatment of Raynaud's phenomenon and disease
  • Treatment of benign prostatic hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Selective inhibition of postsynaptic alpha-1-adrenoreceptors
  • Lowering of blood pressure in supine and standing positions
  • Reduction in left ventricular filling pressure
  • Augmentation of cardiac output
  • Improvement of urinary pressure profile

Dosage & Administration

  • Initial therapy with low starting dose
  • Dosage adjustment based on patient's response
  • Use with diuretic or adrenergic beta-blocking agent for enhanced efficacy
  • Different dosages for patients with renal impairment

Interaction

  • No adverse drug interaction reported with certain medications

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Weakness
  • Palpitations
  • Nausea
  • Liver function abnormalities
  • Edema
  • Orthostatic hypotension
  • Diarrhea
  • Constipation
  • Abdominal discomfort
  • Dry mouth
  • Blurred vision
  • Impotence

Pregnancy & Lactation

  • No teratogenic effects seen in animal testing
  • Caution advised when administered to nursing mothers

Precautions & Warnings

  • Potential for postural hypotension
  • Careful adjustment of diuretic dosage in left ventricular failure patients
  • Close monitoring of blood pressure in patients taking medications known to lower blood pressure

Use in Special Populations

  • Not recommended for children under 12 years
  • Not recommended for certain conditions in left ventricular failure patients

Overdose Effects

  • Accidental ingestion results in drowsiness and depressed reflexes
  • Support of cardiovascular system is of first importance in case of hypotension

Therapeutic Class

  • Alpha adrenoceptor blocking drugs

Storage Conditions

  • Store below 30°C
  • Keep away from light and moisture
  • Keep away from reach of children

Related Brands