Olmenor AM 5 mg+20 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Delta pharma ltd |
| Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized therapy based on baseline blood pressure and target goal
Pharmacology
- Amlodipine is a dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells than on cardiac muscle cells
- Acts as a peripheral arterial vasodilator
- Olmesartan Medoxomil blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II
- Selective blocker of the AT1 receptor
Dosage & Administration
- Substitute individually titrated components
- Initial therapy with 5/20 mg once daily for 1 to 2 weeks
- Titration up to a maximum of 10/40 mg once daily
- Recommended starting dose of Amlodipine is 2.5 mg for elderly patients
Interaction
- Attenuation of antihypertensive effect by NSAIDs including selective COX-2 inhibitors
- Close monitoring of blood pressure, renal function, and electrolytes for patients on combination therapy
Contraindications
- Cannot be co-administered with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Should not be used in 2nd and 3rd trimester
- Potential for adverse effects on the nursing infant
Precautions & Warnings
- Caution for hypotension in volume- or salt-depleted patients
- Risk of vasodilation in patients with severe aortic stenosis
- Increased risk of angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety or effectiveness observed between subjects 65 years of age or older and younger subjects
Overdose Effects
- No information on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children