Olmenor AM 5 mg+40 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Delta pharma ltd |
| Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized blood pressure goals
Pharmacology
- Dihydropyridine calcium channel blocker
- Inhibits transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle
- Peripheral arterial vasodilator
- Selective blocking of angiotensin II
- Does not inhibit ACE
Dosage & Administration
- Initial therapy with 5/20 mg once daily for 1 to 2 weeks
- Titration up to a maximum of 10/40 mg once daily
- Recommended starting dose of Amlodipine is 2.5 mg in patients 75 years
- Not recommended in patients >75 years old
Interaction
- Antihypertensive effect may be attenuated by NSAIDs including selective COX-2 inhibitors
- Close monitoring of blood pressure, renal function and electrolytes
Contraindications
- Cannot be co-administered with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Not to be used in 2nd and 3rd trimester
- Discontinue if pregnancy is detected
- Unknown excretion in human milk
- Consideration for nursing mothers
Precautions & Warnings
- Risk for hypotension in volume- or salt-depleted patients
- Risk of vasodilation in patients with severe aortic stenosis
- Risk of increased angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety or effectiveness observed in subjects 65 years of age or older
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of reach of children