Vastarel MR 35 mg (Tablet (Modified Release))

Unit Price: ৳ 12.00 (2 x 30: ৳ 720.00)
Strip Price: ৳ 360.00

Medicine Details

Category Details
Generic Trimetazidine dihydrochloride
Company Servier bangladesh operation

Indications

  • Add-on therapy for stable angina pectoris
  • Inadequately controlled by first-line antianginal therapies

Pharmacology

  • First 3-keto acyl CoA thiolase inhibitor
  • Metabolic anti-ischemic agent
  • Inhibition of fatty acid pathway
  • Transfer of oxygen to glucose pathway
  • Increase in heart's activity

Dosage & Administration

  • Recommended dose: 35 mg twice daily or 20 mg thrice daily during meals
  • Assessment of treatment benefit after three months
  • Discontinuation in absence of treatment response

Interaction

  • No reported drug interaction
  • No interaction with beta-blockers, calcium antagonists, nitrates, heparin, hypolipidemic agents, or digitalis preparation

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Parkinson's disease or symptoms
  • Tremors, restless legs movement disorders
  • Severe renal impairment

Side Effects

  • Safe and well tolerated
  • Common side effects: dizziness, headache, abdominal pain, diarrhea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria, asthenia

Pregnancy & Lactation

  • No data on use in pregnant women
  • Preferable to avoid use during pregnancy
  • Unknown excretion in human milk
  • Risk to newborns/infants cannot be excluded
  • Avoid use during breastfeeding

Precautions & Warnings

  • Not curative treatment for angina attacks
  • Not initial treatment for unstable angina pectoris
  • Not treatment for myocardial infarction

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of the reach of children

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