Esoclip 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Esomeprazole
Company Guardian healthcare ltd

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Extensively metabolized in the liver
  • Plasma elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Dosage for Healing of Erosive Esophagitis
  • Dosage for Symptomatic GERD
  • Dosage for Helicobacter Pylori eradication
  • Dosage for Zollinger-Ellison Syndrome
  • Dosage for Acid-related Dyspepsia
  • Dosage for Duodenal and Gastric ulcers
  • Dosage for pediatric and adult patients

Administration

  • Tablet or capsule should be swallowed whole
  • Oral Suspension should be stirred and taken with or without water
  • IV Injection should be administered over a specific period
  • Nasogastric or gastric tube administration

Interactions

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Inhibition of gastric acid secretion may interfere with drug absorption
  • No clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Breast-feeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response to therapy does not rule out the presence of gastric malignancy
  • Specific instructions for taking capsules
  • Use of antacids
  • Administration for patients with difficulty swallowing

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy observed in the elderly
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in renal impairment

Overdose Effects

  • Lethal dose observed in animal studies
  • Major signs of acute toxicity
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions

  • Uses of Esoclip 20 mg Capsule
  • Side effects of Esoclip 20 mg Capsule
  • Pregnancy and breastfeeding considerations
  • Time for Esoclip 20 mg Capsule to work
  • Quick tips for taking Esoclip 20 mg Capsule

Related Brands