Emglif 10 mg (Tablet)

Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00

Medicine Details

Category Details
Generic Empagliflozin
Company Orion pharma ltd
Also available as
Emglif 25 mg tablet

Indications

  • Adjunct to diet and exercise for glycemic control in adults with type 2 diabetes mellitus
  • To reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease

Pharmacology

  • Sodium glucose co-transporter-2 (SGLT-2) inhibitor
  • Reduces renal absorption of glucose
  • Increases glucose excretion
  • Contributes to reduced hyperglycaemia
  • Assists in weight loss
  • Reduces blood pressure

Dosage & Administration

  • Recommended daily dose of 10 mg
  • May be increased to 25 mg once daily in patients tolerating it
  • To be taken in the morning
  • Can be taken with or without food
  • Correction of volume depletion recommended prior to initiation

Interaction

  • Co-administration with diuretics increases urine volume
  • Co-administration with insulin or insulin secretagogues increases the risk for hypoglycemia
  • Monitoring glycemic control with urine glucose tests is not recommended
  • Interference with 1,5-anhydroglucitol (1,5-AG) assay

Contraindications

  • History of serious hypersensitivity reaction to empagliflozin or any of its ingredients
  • Severe renal impairment
  • End-stage renal disease
  • Dialysis

Side Effects

  • Urinary tract infections
  • Female genital mycotic infections
  • Dehydration
  • Hypotension
  • Weakness
  • Dizziness
  • Increased thirstiness

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to fetus
  • Not recommended when breastfeeding

Precautions & Warnings

  • Assessment of renal function recommended prior to initiation
  • Not initiated in patients with eGFR less than 45 ml/min/1.73 m^2
  • No dose adjustment needed in patients with eGFR greater than or equal to 45 ml/min/1.73 m^2

Overdose Effects

  • Supportive measures recommended in case of overdose
  • Hemodialysis not studied for removal of empagliflozin

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C23H27ClO7

Common Questions about Emglif 10 mg Tablet

  • Reduces reabsorption of glucose from the kidney
  • Improves glycemic control in adults
  • Unsafe to use during pregnancy
  • Unsafe to use during breastfeeding
  • Should be used cautiously in patients with an underlying kidney disease
  • No dose adjustment needed for patients with mild to moderate liver disease
  • Used alone or together with other diabetes medicines to control blood sugar and avoid long-term complications
  • May cause dehydration, hypoglycemia, genital fungal and/or urinary tract infections, so practice good hygiene
  • Need to monitor blood sugar regularly while taking this tablet
  • Inform doctor immediately in case of certain symptoms

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