Bactacef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category	Details
Generic	Cephradine
Company	Silco pharmaceutical ltd
Also available as	Bactacef 500 mg capsule Bactacef ds 250 mg suspension

Indications

Treatment of upper respiratory tract infections
Treatment of lower respiratory tract infections
Treatment of urinary tract infections
Treatment of skin and soft tissue infections
Effective against Staphylococci infections
Effective against Streptococci infections
Effective against Escherichia coli infections
Effective against Klebsiella spp infections
Effective against Proteus mirabilis infections
Effective against Haemophilus influenza infections
Effective against Shigella spp infections
Effective against Salmonella spp infections
Effective against Neisseria spp infections

Pharmacology

Semisynthetic broad-spectrum bactericidal antibiotic
Active against both gram-positive and gram-negative microorganisms
Inhibits cross-linking process in cell wall of bacteria
Causes lysis of bacteria due to external osmotic pressure

Dosage & Administration

Recommended oral dosage for adults with urinary tract infections
Recommended oral dosage for adults with respiratory tract infections
Recommended oral dosage for adults with skin and soft tissue infections
Recommended oral dosage for children with otitis media
Maximum daily dosage
Dosage adjustment in renal impairment
Recommended injectable dosage for adults
Recommended injectable dosage for children
Prophylactic dose for preoperative use

Interaction

Nephrotoxic drug interaction risk
Enhanced risk of renal toxicity with diuretics
Enhanced risk of renal toxicity with probenecid

Contraindications

Contraindicated in patients with hypersensitivity to cephalosporins

Side Effects

Gastrointestinal disturbances
Hypersensitivity phenomena
Skin reactions
Rare side effects like glossitis and dizziness
Rare side effects like fever and serum sickness
Rare side effects like confusion and sleep disturbances
Rare side effects like reversible interstitial nephritis
Rare side effects like elevation of blood urea nitrogen

Pregnancy & Lactation

Caution required due to excretion in breast milk
Potential risk of dizziness in patients

Precautions & Warnings

Potential risk of superinfection with prolonged use
Risk of cross-sensitivity to penicillins
Potential positive result in Coombs' testing
Potential false positive urine glucose result
Lactose content caution for patients with specific intolerances

Use in Special Populations

Dosing recommendations for patients with renal impairment
Higher doses may be required for chronic or severe infections

Overdose Effects

Non-specific symptoms like nausea and vomiting
Supportive treatment required
Gastric lavage for large ingestions

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Recommendations for storage of Bactacef Suspension
Recommendations for storage of Bactacef Injection solutions

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