Bactacef DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 120.00

Medicine Details

Category Details
Generic Cephradine
Company Silco pharmaceutical ltd
Also available as
Bactacef 500 mg capsule Bactacef 125 mg suspension

Title

  • Bactacef DS

Categories

  • Medicine
  • Antibiotics
  • Cephalosporins

Description

  • A broad-spectrum bactericidal antibiotic for the treatment of various infections caused by sensitive Gram-positive and Gram-negative bacteria.

Gram-Positive Infections

  • Sinusitis
  • Pharyngitis
  • Tonsillitis
  • Laryngo-tracheo bronchitis
  • Otitis media

Gram-Negative Infections

  • Bronchitis (acute and chronic)
  • Lobar pneumonia
  • Bronchopneumonia
  • Cystitis
  • Urethritis
  • Pyelonephritis
  • Skin abscess
  • Cellulitis
  • Furunculosis
  • Impetigo

Microorganisms Susceptible

  • Staphylococci
  • Streptococci
  • Escherichia coli
  • Klebsiella spp
  • Proteus mirabilis
  • Haemophilus influenza
  • Shigella spp
  • Salmonella spp
  • Neisseria spp

Active Ingredient

  • Cephradine

Pharmacological Action

  • Bactericidal effect on both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell wall

Dosage Forms

  • Oral capsules
  • Injectable solutions

Dosage & Administration

  • Adults: Urinary tract infections - 500mg-1g four times daily
  • Respiratory tract infections - 250-500mg four times daily
  • Children: Dosage based on weight and infection type
  • Elderly and Renal Impairment: Dose adjustment required

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Blood disorders
  • Liver enzyme disturbances
  • Reversible interstitial nephritis

Pregnancy & Lactation

  • Use with caution in lactating mothers
  • Potential for dizziness, caution while operating machinery

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Cross-sensitivity with penicillins
  • False positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose, not suitable for certain patients

Special Populations

  • Dosing recommendations for renal impairment and haemodialysis patients
  • Higher doses may be required for severe or chronic infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, diarrhoea

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Reconstituted suspension to be used within 7-14 days
  • Injection solutions to be used within 2 hours at room temperature
  • Retains potency for 12 hours when stored at 5°C
  • Keep out of reach of children

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