Cefusil 500 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Cefuroxime axetil |
Company | Silco pharmaceutical ltd |
Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by various pathogens
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease caused by Borrelia burgdorferi
Pharmacology
Cefuroxime is a well-characterized and effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains
Dosage
- Tablet or Suspension:
- Adolescents and adults (13 years and older):
- 250 mg b.i.d. for various durations for different infections
- Paediatric Patients (3 months to 12 years):
- 20 mg/kg/day b.i.d. for various durations for different infections
- Adolescents and adults (13 years and older):
- Parenteral:
- Adult:
- 750 mg three times daily by IM or IV injection for severe infections
- 1.5 gm three times daily by IV injection if necessary
- 1.5 gm by IV injection at induction of anaesthesia for surgical prophylaxis
- 1.5 gm IV injection twice daily for pneumonia
- 750 mg twice daily (IM or IV injection) for 2-3 days for acute exacerbations of chronic bronchitis
- 1.5 gm IV injection four times daily for bone and joint infections
- 3 gm IV injection three times daily for Meningitis
- Children (above 3 months of age):
- 30 - 100 mg/kg/day given in 3 or 4 equally divided doses for various infections
- 200-240 mg/kg/day by IV injection in 3 or 4 divided doses for Meningitis
- Adult:
Administration
The use of freshly reconstituted solution is recommended. It maintains potency for at least 24 hours at room temperature or 48 hours at 5o C
Interaction
No potentially hazardous interactions have been reported
Contraindications
Cefuroxime is contraindicated in patients with known allergy to Cephalosporins
Side Effects
Adverse effects to Cefusil have occurred infrequently and have been generally mild and transient in nature. Effects reported include rashes and gastrointestinal disturbances
Pregnancy & Lactation
US FDA pregnancy category of Cefuroxime is B. Caution should be exercised when Cefuroxime is administered to a nursing woman
Precautions & Warnings
Cefusil should be given with care to patients receiving concurrent treatment with potent diuretics & who have a history of colitis
Therapeutic Class
Second generation Cephalosporins
Reconstitution
Instructions for reconstituting Cefuroxime for different doses and methods of injection
Storage Conditions
Store in a cool, dry place (below 30o C), away from light & moisture, keep out of the reach of children
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