Naxsil 500 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Silco pharmaceutical ltd |
Indications
- Relief of rheumatoid arthritis
- Relief of osteoarthritis
- Relief of ankylosing spondylitis
- Relief of juvenile arthritis
- Relief of tendonitis
- Relief of bursitis
- Relief of acute gout
- Management of primary dysmenorrhea & pain
Pharmacology
- Blockage of COX-1 and COX-2 enzymes
- Decreased prostaglandin synthesis
- Antipyretic properties
- Analgesic properties
- Anti-inflammatory properties
- Unique functional differences between COX-1 and COX-2 enzymes
Dosage & Administration
- Oral administration with water
- Preferably taken after meals
- Specific dosages for different indications
- Administration in children
- Application instructions for gel
Interaction
- Diminished antihypertensive effect with ACE inhibitors
- Delayed absorption with Antacids & Sucralfate
- Increased adverse effects with Aspirin
- Reduced natriuretic effect with Diuretics
- Enhanced toxicity with Methotrexate
- Increased risk of GI bleeding with Warfarin and Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal side effects
- Central Nervous System side effects
- Dermatological side effects
- Cardiovascular side effects
- Other reported side effects
Pregnancy & Lactation
- Adverse effects on the fetus
- Delay in parturition
- Premature closure of the ductus arteriosus
- Severe pulmonary hypertension in infants
- Excretion in breast milk
Precautions & Warnings
- Renal effects
- Long-term administration results in renal papillary necrosis
- Acute interstitial nephritis
- Hematuria
- Proteinuria
- Nephrotic syndrome
- Elimination by the kidneys
- Use with caution in patients with impaired renal function
- Hepatic effects
- Reports of jaundice
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Temperature below 30°C
- Protected from light & moisture
- Keep out of the reach of children