Peplo 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (10 x 6: ৳ 480.00)

Strip Price: ৳ 48.00

Medicine Details

Treatment of gastric and duodenal ulcer
Treatment of NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Treatment of gastro-esophageal reflux disease
Long-term management of acid reflux disease
Treatment of acid-related dyspepsia
Treatment of severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Treatment of Zollinger-Ellison syndrome
Treatment of Helicobacter pylori-induced peptic ulcer

Direction for use of IV Injection
Direction for use of IV Infusion
IV injection should be given as a slow intravenous injection
IV infusion should be given as an intravenous infusion over a period of 20-30 minutes or more
Reconstituted solution should not be mixed or co-administered with any other drug in the same infusion set

Decreased intragastric acidity may reduce the absorption of ketoconazole
Metabolized in the liver through cytochrome P450
Can delay the elimination of diazepam, phenytoin, and warfarin
Plasma concentrations of Peplo and clarithromycin are increased during concomitant administration
No evidence of an interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, or antacids
Absorption not affected by alcohol or food
Concomitant treatment with digoxin leads to a 10% increase in the bioavailability of digoxin

Known hypersensitivity to Omeprazole
Suspicion of gastric ulcer should exclude the possibility of malignancy before treatment

Mild and reversible adverse reactions
Skin rash, urticaria, and pruritus reported
Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia reported in isolated cases
Diarrhea and headache reported
Gastrointestinal reactions including constipation, nausea/vomiting, flatulence, and abdominal pain
Other reactions include dry mouth, stomatitis, candidiasis, paraesthesia, dizziness, light headedness, and feeling faint
Reversible mental confusion, agitation, depression, and hallucinations reported predominantly in severely ill patients
Arthritic and myalgic symptoms reported
Isolated cases of vision disturbance, taste disturbance, peripheral edema, and increased sweating
Isolated cases of leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock, malaise, fever, bronchospasm, encephalopathy, hepatitis, interstitial nephritis, and hepatic failure
Increases in liver enzymes observed

No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
Omeprazole can be used during pregnancy
No information available on the passage of Omeprazole into breast milk or its effects on the neonate
Breast-feeding should be discontinued if the use of Omeprazole is essential

Avoid concomitant use of clopidogrel and Peplo
Observational studies suggest PPI therapy may be associated with an increased risk for osteoporosis-related fractures
Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term treated patients
Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities