Rebalin 50 mg (Capsule)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Silco pharmaceutical ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It binds with high affinity to the alpha2-delta site in central nervous system tissues, contributing to its anti-nociceptive and antiseizure effects.
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day for neuropathic pain associated with diabetic peripheral neuropathy
- Recommended dose for postherpetic neuralgia is 75 to 150 mg two times a day or 50 to 100 mg three times a day
- For fibromyalgia, the recommended dose is 300 to 450 mg/day
- The recommended dose for neuropathic pain associated with spinal cord injury ranges from 150 to 600 mg/day
Administration
- Route of administration: Oral route, to be taken with or without food
- Special administration for Pregabalin CR tablet: Administered after an evening meal, should be swallowed whole and not split, crushed or chewed
Interaction
- Drug interaction with medication: Unlikely to be involved in significant pharmacokinetic drug interactions
- Drug interaction with food and others: Not applicable
Contraindications
Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal (primarily difficulty with concentration/attention)
- Increased weight and increased appetite in pediatric patients
Pregnancy & Lactation
- Pregnancy: No adequate and well-controlled studies in pregnant women, potential risk to fetus
- Lactation: Small amounts detected in the milk of lactating women, breastfeeding not recommended
Precautions & Warnings
- Risk of angioedema, hypersensitivity reactions, and suicidal thoughts or behavior
- Potential for respiratory depression when used with concomitant CNS depressants
- May cause dizziness and somnolence, impairing ability to drive or operate machinery
- Risk of increased seizure frequency or other adverse reactions if rapidly discontinued
- Potential to cause peripheral edema, caution when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Use in children and adolescents: Safety and effectiveness not established for various conditions
- Pediatric patients for the treatment of partial onset seizures: Safety and effectiveness not established for those below the age of 1 month
- Safety and effectiveness of Rebalin extended-release tablet: Not established for pediatric patients
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Agitation and restlessness
- Seizures and heart block
- No specific antidote, general supportive care indicated
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions about Rebalin 50 mg Capsule
- First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Duration of use depends on improvement in health conditions
- Should be taken after food in a prescribed dosage
- Instructions for storage and disposal
- Variations in working for different diseases
- Duration of use depends on the specific condition
- Continued use even if feeling fine
- Possible concomitant use with Diazepam
- Potential for weight gain, necessitating consultation with a dietician
- Quick tips for usage