Axicef Plus (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 280.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Unimed unihealth pharmaceuticals ltd
Also available as
Axicef plus 250 mg tablet Axicef plus 500 mg tablet

Title

  • Axicef Plus 125 Suspension

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

  • Axicef Plus is indicated for the treatment of infections caused by sensitive bacteria.
  • Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms.
  • Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus.

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae, caused by various bacteria like Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, E. coli
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Septicemia caused by various bacteria
  • Meningitis caused by various bacteria
  • Switch therapy (Injectable to oral)

Pharmacology

  • Bactericidal action of Cefuroxime against Gram-positive and Gram-negative organisms by interfering with the transpeptidation process
  • Clavulanic acid provides protection of Cefuroxime from degradation by beta lactamase enzymes

Dosage & Administration

  • Dosage specified for various infections in adolescents, adults, and pediatric patients

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the serum concentration
  • Drug reducing gastric acidity may result in lower bioavailability of Cefuroxime

Contraindications

  • Patients with known allergy to cephalosporin
  • Patients with Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Rarely renal dysfunction, anaphylaxis, angioedema, pruritis, rash, urticaria

Pregnancy & Lactation

  • Safe for later pregnancy to treat urinary and other infections
  • Excreted into breast milk in small quantities

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • Given with care to patients with history of colitis

Storage Conditions

  • Store in a cool, dry place below 30°C, away from light and moisture
  • Keep out of the reach of children

Therapeutic Class

  • Second generation Cephalosporins

FAQ

  • What is Axicef Plus 125 Syrup?
  • What is Axicef Plus 125 Syrup used for?
  • How long does it take for Axicef Plus 125 Syrup to take effect?
  • How long do the effects of this medicine last?
  • Is Axicef Plus 125 Syrup it safe to consume alcohol while taking this medicine?
  • Is Axicef Plus 125 Syrup a habit forming medicine?
  • Can this medicine be taken during pregnancy?
  • Can Axicef Plus 125 Syrup be taken while breast-feeding?
  • Quick Tips like finishing the full course of treatment, taking with food, and consulting doctor for antibiotic use

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