Cytopag 25 mg (Tablet)
Unit Price: ৳ 500.00 (1 x 5: ৳ 2,500.00)
Strip Price: ৳ 2,500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Eltrombopag olamine |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of thrombocytopenia in patients with persistent or chronic immune thrombocytopenia
- Treatment of thrombocytopenia in patients with hepatitis C infection
- Treatment of severe aplastic anemia
Pharmacology
- Eltrombopag Olamine is a small molecule thrombopoietin (TPO) receptor agonist
- Interacts with the transmembrane domain of the human TPO-receptor
- Induces signaling cascades for increased platelet production
Dosage & Administration
- Route of administration: Oral
- Can be taken with or without a low-calcium meal
- Dosage varies for different conditions and age groups
- Adjustable dosing for persistent or chronic immune thrombocytopenia
- Specific dosing for hepatitis C associated thrombocytopenia
Drug Interaction
- Take eltrombopag at least 2 hours before or 4 hours after medications containing polyvalent cations
- Time-specific interaction with calcium-rich foods
Contraindications
- Contraindicated in patients with known hypersensitivity to eltrombopag or its components
Side Effects
- Common side effects include anemia, nausea, pyrexia, ALT increased, cough, fatigue, headache, diarrhea
Pregnancy & Lactation
- Insufficient data for assessing drug-associated risks in pregnancy
- Not recommended during breastfeeding due to potential adverse reactions
Precautions & Warnings
- Increased risk in patients with chronic hepatitis C in combination with interferon and ribavirin
- Monitor liver function and platelet counts regularly
Use in Special Populations
- Safety and efficacy in pediatric patients below 1 year not established
- Safety and efficacy not established in pediatric patients with specific conditions
Overdose Effects
- Excessive increase in platelet counts leading to thrombotic or thromboembolic complications
- Consider oral administration of metal cation containing preparation in case of overdose
Therapeutic Class
Haemostatic drugs
Storage Conditions
Store in a cool (below 25°C) and dry place protected from light