Lamitrin 2 mg (Dispersible Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Lamotrigine |
| Company | Aci limited |
| Also available as |
Indications
- Adjunctive therapy for partial-onset seizures
- Adjunctive therapy for primary generalized tonic-clonic seizures
- Adjunctive therapy for generalized seizures of Lennox-Gastaut syndrome
- Monotherapy for epilepsy in patients aged 16 years and older
- Treatment of bipolar disorder in patients aged 18 years and older
Description
- Phenyltriazine antiepileptic
- Treatment for some types of epilepsy and bipolar disorder
- Controls epileptic seizures by inhibiting voltage-sensitive sodium channels
- Stabilizes neuronal membranes to inhibit neurotransmitter release
Pharmacology
- Inhibits voltage-sensitive sodium channels
- Modulates release of presynaptic excitatory neurotransmitters
- Binds weakly to various receptors such as serotonin, adenosine, dopamine, GABA, and histamine
- Inhibits Cav2.3 (R-type) calcium currents
Dosage & Administration
- Escalation regimen for patients with epilepsy aged 2 years and older
- Escalation regimen for patients with bipolar disorder aged 18 years and older
- Initial weight-based dosing guide for pediatric patients with epilepsy
- Usual maintenance dose for different patient groups
Interaction
- Impact of valproate, carbamazepine, phenytoin, phenobarbital, rifampin, estrogen-containing oral contraceptives, protease inhibitors on Lamitrin concentrations
Side Effects
- Adult side effects: dizziness, headache, diplopia, nausea, blurred vision, rash
- Children side effects: vomiting, diarrhea, infection, fever, abdominal pain, tremor
Pregnancy & Lactation
- Pregnancy category C
- Excretion in human milk
- Consideration for nursing mothers
Precautions & Warnings
- Discontinue at the first sign of rash
- Monitoring for blood dyscrasias, suicidal behavior, ideation, and aseptic meningitis
Use in Special Populations
- Safety and effectiveness in pediatric patients with epilepsy and bipolar disorder
Overdose Effects
- Ataxia, nystagmus, seizures, decreased level of consciousness, coma, intraventricular conduction delay
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Keep out of reach of children
- Store in a dry place
- Below 25°C temperature
- Protected from light