Oxima Plus 110 mcg+50 mcg (Inhalation Capsule)
Unit Price: ৳ 35.00 (2 x 10: ৳ 700.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Indacaterol glycopyrronium |
| Company | Aci limited |
Indications
- Long-term once-daily maintenance bronchodilator treatment for COPD patients
- Not indicated for acute episodes of bronchospasm
- Not indicated for asthma
Composition
- Each dry powder inhaler capsule contains Indacaterol 110 mcg as Indacaterol Maleate INN
- Each dry powder inhaler capsule contains Glycopyrronium 50 mcg as Glycopyrronium Bromide BP
Pharmacology
- Combination of Glycopyrronium (an anticholinergic) and Indacaterol (a LABA)
- Stimulation of intracellular adenyl cyclase for bronchial smooth muscle relaxation
- Pharmacological effects through inhibition of M3 receptor at the smooth muscle for bronchodilation
Dosage & Administration
- 1 inhalation once daily for maintenance treatment of COPD in adults
- Use at the same time every day
- Usable for geriatric patients but not for children and adolescents
- Usable in patients with mild to moderate renal or hepatic impairment
- Use cautiously in patients with severe renal or hepatic impairment
Interaction
- Contraindicated with β-adrenergic blockers, anticholinergics, or sympathomimetic agents
- Caution with hypokalemic treatment
Contraindications
- Hypersensitivity to Glycopyrronium or Indacaterol or any other component
- Severe hypersensitivity to milk proteins
- Contraindicated in patients with asthma without long-term asthma control medication
Side Effects
- Cardiovascular effects, ocular disorders, urinary retention
- Gastrointestinal disorders, dry mouth, cough
- Immediate hypersensitivity reactions, cardiovascular effects, hypokalemia
- Headache, nervousness, insomnia, muscle spasms, fatigue, malaise, tremor
- Common adverse drug reactions include cough and oropharyngeal pain
Pregnancy & Lactation
- Pregnancy category C
- Use during pregnancy only if expected benefit justifies potential risk to the fetus
- Consideration for use during lactation only if expected benefit to the woman is greater than any possible risk to the infant
Precautions & Warnings
- Increased risk of serious asthma-related events with LABA monotherapy
- Do not initiate in acutely deteriorating COPD or asthma
- Use with caution in patients with cardiovascular disorders, convulsive disorders, diabetes mellitus, and thyrotoxicosis
- Worsening of narrow-angle glaucoma and urinary retention may occur
- Be alert to hypokalemia and hyperglycemia
Overdose Effects
- No information on clinically relevant overdosing with the product
- Supportive and symptomatic treatment indicated for overdose effects
- Hospitalization recommended for serious cases
Therapeutic Class
- Combined bronchodilators
Storage Conditions
- Avoid storage in direct sunlight or heat
- Store in a cool & dry place
- Keep away from eyes
- Keep all medicines out of reach of children