Vistarin 6000 Anti-Xa IU/0.6 ml (SC Injection)

0.6 ml pre-filled syringe: ৳ 575.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Aci limited
Also available as
Vistarin 4000 anti xa injection Vistarin 8000 anti xa injection Vistarin 2000 anti xa injection

Title

  • Vistarin Enoxaparin Sodium BP 20 mg Pre-Filled Syringe
  • Vistarin Enoxaparin Sodium BP 40 mg Pre-Filled Syringe
  • Vistarin Enoxaparin Sodium BP 60 mg Pre-Filled Syringe
  • Vistarin Enoxaparin Sodium BP 80 mg Pre-Filled Syringe

Categories

  • Medicine
  • Thrombosis treatment
  • Angina treatment
  • Myocardial infarction treatment
  • Anticoagulant
  • Hemodialysis prevention
  • Surgical prophylaxis
  • Medical prophylaxis
  • Parenteral anti-coagulant

Description

  • Low molecular weight heparin
  • High anti-Xa activity
  • No notable modification of activated Partial Thromboplastin Time (aPTT)
  • Primarily metabolised in the liver
  • Suitable for subcutaneous administration
  • No influence on platelet aggregation
  • Protects from thrombus formation in the extra-corporal circulation
  • Prevents venous thromboembolic disease
  • Instructions for self-injection
  • Disposal instructions for used syringes
  • Pregnancy category B
  • Caution in conditions with increased potential for bleeding
  • Dose adjustments based on renal impairment
  • Protamine sulfate can neutralize accidental overdosage

Composition

  • Enoxaparin Sodium BP 20 mg equivalent to 2000 anti-Xa III
  • Enoxaparin Sodium BP 40 mg equivalent to 4000 anti-Xa III
  • Enoxaparin Sodium BP 60 mg equivalent to 6000 anti-Xa IU
  • Enoxaparin Sodium BP 80 mg equivalent to 8000 anti-Xa IU

Mode of Action

  • Low anti-lla or antithrombin activity
  • No increase in bleeding time
  • No influence on platelet aggregation
  • No notable modification of activated Partial Thromboplastin Time (aPTT)
  • Primarily metabolised in the liver

Dosage

  • Subcutaneously administered
  • Twice daily dosage for deep vein thrombosis treatment
  • Oral anticoagulant therapy initiation
  • Concurrent administration with aspirin for angina treatment
  • Recommended dose for prevention of thrombus formation in hemodialysis
  • Different dosages for surgical prophylaxis based on risk
  • Subcutaneously administered for prophylaxis in medical patients

Administration

  • Subcutaneous and intravascular routes
  • No intramuscular administration
  • Instructions for self-injection with pre-filled syringes
  • Selecting the appropriate dose based on body weight
  • Safe disposal instructions for used syringes

Interaction

  • Discontinuation of agents affecting hemostasis prior to Vistarin therapy
  • Careful clinical and laboratory monitoring for indicated combinations

Contraindications

  • Hypersensitivity to Enoxaparin Sodium, heparin, or other low molecular weight heparins
  • Active major bleeding
  • High risk of uncontrolled hemorrhage including recent hemorrhagic stroke

Side Effects

  • Haemorrhage (bleeding)
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Skin reactions at injection sites
  • Neuraxial hematomas with concurrent use of Vistarin and spinal/epidural anesthesia

Pregnancy & Lactation

  • Pregnancy category B
  • No evidence of crossing the placental barrier
  • Caution and careful consideration for breastfeeding mothers

Precautions & Warnings

  • Deep subcutaneous route for prophylactic and curative treatment
  • Platelet count measurement before initiation of treatment
  • Use with caution in conditions with increased potential for bleeding

Use in Special Populations

  • No dosage adjustment in elderly patients unless kidney function is impaired
  • Observation for signs and symptoms of bleeding in patients with renal impairment

Overdose Effects

  • Hemorrhagic complications in case of accidental overdosage
  • Neutralization by slow i.v. injection of protamine sulfate

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Cool, dry place
  • Protection from light and moisture
  • Temperature not to exceed 25°C
  • Keep out of reach of children

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