Silclog 75 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel bisulphate |
| Company | Silco pharmaceutical ltd |
Title and Categories
- Silclog Tablet
- Medicine
- Pharmaceutical
Dimensions
- N/A
Color Options
- White
Functions
- Reducing the rate of myocardial infarction (MI)
- Reducing the rate of stroke
- Inhibiting platelet activation and aggregation
Materials
- Clopidogrel
- Prodrug
Technical Specifications
- 75 mg dosage
- Platelet aggregation inhibition 2 hours after oral dose
- Dose-dependent inhibition of platelet aggregation
- Steady state inhibition between Day 3 and Day 7
Design Elements
- Oral tablets
Usability Features
- Oral administration
- Can be taken with or without food
Interaction
- Increases risk of bleeding when used with NSAIDs, warfarin, SSRIs, SNRIs
- Avoid concomitant use with CYP2C19 inhibitors like omeprazole or esomeprazole
- Avoid concomitant use with Repaglinide as it increases plasma concentrations of Repaglinide
Contraindications
- Hypersensitivity to the drug substance
- Active pathological bleeding such as peptic ulcer or intracranial hemorrhage
Side Effects
- Common side effects: Bleeding, Diarrhoea, gastrointestinal discomfort, haemorrhage, Skin reactions
- Rare side effects: Acquired haemophilia, anaemia, angioedema, arthralgia, arthritis, bone marrow disorders
Pregnancy & Lactation
- Use during pregnancy only if clearly needed
- Unknown excretion in human breast milk
- Decision should consider the importance of the drug to the mother
Precautions & Warnings
- Metabolism impairment by genetic variations and drugs inhibiting CYP2C19
- Risk of bleeding due to lifetime platelet aggregation inhibition
- Discontinuation increases the risk of cardiovascular events
- Reported cases of Thrombotic Thrombocytopenic Purpura (TTP)
- Reported cases of hypersensitivity
Use in Special Populations
- Safety and effectiveness in pediatric populations not established
- No dosage adjustment necessary in elderly patients
Overdose Effects
- May lead to bleeding complications
- Platelet transfusion may restore clotting ability
Therapeutic Class
- Anti-platelet drugs
Storage Conditions
- Keep below 30°C temperature in a dry place
- Protected from light
- Do not freeze
- Keep out of the reach of children